Department of Epidemiology and Biostatistics, School of Public Health (Dr Zhong, Ms Zhang, Dr Zhang, Mr Jiang, Dr Liang, Dr Huang); Ma'anshan Center for Disease Control and Prevention, Ma'anshan (Dr Qin, Mr Chen); and Experimental Center Platform for Physical and Chemical (Dr Huang), Anhui Medical University, Hefei, Anhui, P.R. China.
J Occup Environ Med. 2019 Apr;61(4):271-277. doi: 10.1097/JOM.0000000000001511.
As a widespread toxic metal, arsenic had potential effect for hypertensive. We evaluated the association between urinary arsenic and the incidence of hypertension in adult residents along the Yangtze River of China.
We conducted the study of 1358 adults 18 to 74 years of age from Chizhou, Maanshan, and Tongling of Anhui province, who participated in the baseline study in 2014 to 2015. Inductively coupled plasma optical emission spectrometry was used to measure urinary as of residents, and follow-up extended through 2016 to 2017.
We identified 275 hypertension events. The hazard ratios (HRs) of highest quartile arsenic compared with lowest quartile was 1.49 for hypertension events (95% confidence interval [CI] = 1.05 to 2.12), and HRs (≥P20 vs <P20) was 1.37 (95% CI = 1.02 to 1.84).
Higher level of arsenic exposure might play a role in increasing the incidence of hypertension.
砷作为一种广泛存在的有毒金属，可能对高血压有潜在影响。我们评估了中国长江流域成年居民尿液砷与高血压发病率之间的关系。
我们对来自安徽省池州、马鞍山和铜陵的 1358 名 18 至 74 岁的成年人进行了研究，他们参加了 2014 年至 2015 年的基线研究。采用电感耦合等离子体发射光谱法测量居民的尿液砷水平，并在 2016 年至 2017 年进行了随访。
我们确定了 275 例高血压事件。与最低 quartile 相比，最高 quartile 砷的危害比（HRs）为高血压事件的 1.49（95%置信区间[CI] = 1.05 至 2.12），而 HRs（≥P20 与 <P20）为 1.37（95%CI = 1.02 至 1.84）。
较高水平的砷暴露可能在增加高血压发病率方面发挥作用。
