Mahmmood Venus H, Shihab Saif Mohamed
Ghazi Al-Hariry for Specialized Surgeries Hospital, Medical City Complex.
Ministry of Health.
J Craniofac Surg. 2019 May/Jun;30(3):659-662. doi: 10.1097/SCS.0000000000004938.
Temporomandibular disorders (TMD) refer to a group of heterogeneous, pain and dysfunction conditions involving the masticatory system, which influences life quality of the sufferers. Nanofat graft injection in temporomandibular joint (TMJ) is a simple and less invasive surgical procedure for treatment of TMJ problems.The aim of this study was to evaluate influence and effectiveness of nanofat injection in TMJ for treatment of TMD.
This study was performed in Al-Shaheed Ghazi Al-Hariri Hospital, Department of Oral and Maxillofacial Surgery, Baghdad Medical City from October 2016 and December 2017.A total of 11 patients (3 males) and (8 females) with range of age 18 to 34 years old.Every patient was assessed for the following parameters preoperatively: Pain level, maximum mouth opening (MMO), joint clicking, and deviation.
The present study revealed marked female predilection with female ratio about 72.7% (8 patients) and male ratio 27.3% (3 patients), range between 18 and 34 years old. Three patients were presented with single joint (15.8%) and 16 patients were presented with both joints (84.2%).In general, all patients tolerated treatment procedures without any serious complications during the procedure or after the procedure.The results of parameters were pain, clicking, and deviation (P < 0.001 HS) and MMO (P < 0.032-0.041 S).
Nanofat injection in TMJ showed therapeutic benefits, simplicity, safety, lack of significant side effects, and complication.
颞下颌关节紊乱病（TMD）是指一组涉及咀嚼系统的异质性疼痛和功能障碍性疾病，会影响患者的生活质量。颞下颌关节（TMJ）内注射纳米脂肪是一种治疗颞下颌关节问题的简单且侵入性较小的手术方法。本研究的目的是评估纳米脂肪注射到颞下颌关节中治疗颞下颌关节紊乱病的影响和效果。
本研究于2016年10月至2017年12月在巴格达医学城的烈士加齐·哈里里医院口腔颌面外科进行。共有11例患者（3例男性和8例女性），年龄在18至34岁之间。每位患者在术前均评估以下参数：疼痛程度、最大张口度（MMO）、关节弹响和偏斜。
本研究显示明显的女性偏好，女性比例约为72.7%（8例患者），男性比例为27.3%（3例患者），年龄在18至34岁之间。3例患者为单关节受累（15.8%），16例患者为双关节受累（84.2%）。总体而言，所有患者在手术过程中及术后均耐受治疗程序，无任何严重并发症。各参数结果为疼痛、弹响和偏斜（P<0.001，HS）以及最大张口度（P<0.032 - 0.041，S）。
颞下颌关节内注射纳米脂肪显示出治疗益处、操作简单、安全、无明显副作用和并发症。
