Wang Xixiong, Li Zhiqiang, Chen Meizhu, Wu Chenming, Fu Yexiang
Department of Surgical Oncology, Boao Evergrande International Hospital, Qionghai.
Department of Gastrointestinal Surgery, Sanya People's Hospital, Sanya, China.
Medicine (Baltimore). 2018 Nov;97(48):e13419. doi: 10.1097/MD.0000000000013419.
The aim of this study is to find the better treatment for gastric cancer by comparing robotic gastrectomy, laparoscopic gastrectomy, and open gastrectomy using Bayesian network meta-analysis.
We will search PubMed, Embase, and the Cochrane Library for eligible studies published before 1 September 2018. There will be no language restrictions. Randomized clinical trials that compare robotic gastrectomy, laparoscopic gastrectomy, or open gastrectomy for patients with gastric cancer will be included. The risk of bias of included studies will be assessed by the Cochrane Collaboration's tool for assessing risk of bias in randomized trial. The outcomes of the study include operation time, estimated blood loss, time of ambulation, times to first flatus, time of oral intake, hospitalization, and the occurrence of complication. If sufficient data is collected and adequate clinical homogeneity is established among studies, we will conduct pairwise meta-analyses and Bayesian network meta-analyses for all related outcome measures.
The study does not involve human subjects and does not need ethical approval and patient consent. The results of the network meta-analysis will be disseminated in a peer-reviewed journal for publication.
本研究旨在通过使用贝叶斯网络荟萃分析比较机器人胃癌切除术、腹腔镜胃癌切除术和开放胃癌切除术，寻找更好的胃癌治疗方法。
我们将检索PubMed、Embase和Cochrane图书馆，查找2018年9月1日前发表的符合条件的研究。无语言限制。纳入比较机器人胃癌切除术、腹腔镜胃癌切除术或开放胃癌切除术治疗胃癌患者的随机临床试验。纳入研究的偏倚风险将通过Cochrane协作网评估随机试验偏倚风险的工具进行评估。研究结果包括手术时间、估计失血量、下床活动时间、首次排气时间、进食时间、住院时间和并发症的发生情况。如果收集到足够的数据且研究间建立了充分的临床同质性，我们将对所有相关结局指标进行成对荟萃分析和贝叶斯网络荟萃分析。
本研究不涉及人类受试者，无需伦理批准和患者同意。网络荟萃分析的结果将在同行评审期刊上发表。
