Obbarius Alexander, Fischer Kathrin I, Fischer Felix, Liegl Gregor, Obbarius Nina, Nolte Sandra, Rose Matthias
Psychother Psychosom Med Psychol. 2018 Dec;68(12):534-547. doi: 10.1055/a-0764-4691. Epub 2018 Dec 4.
Health-related quality of life (HRQoL) acquires increased importance as a target parameter for different stakeholders in healthcare, e. g. to assess treatment outcome in chronically ill patients. In this educational article, we explain the levels of the health-related quality of life construct and associated main dimensions including physical, mental and social health. State-of-the-art approaches for assessment of patient-reported outcomes (PROs) are introduced on the basis of the HRQoL model. Furthermore, modern test-theoretical approaches and their applications are presented, which are aimed at standardizing and improving the assessment of PROs (e. g., computer-adaptive testing). Finally, we present 2 major international PRO initiatives (PROMIS and EORTC Quality of Life Group) that have been influential in advancing the assessment of patient outcomes over the last few years.
与健康相关的生活质量（HRQoL）作为医疗保健中不同利益相关者的目标参数，其重要性日益增加，例如用于评估慢性病患者的治疗结果。在这篇教育性文章中，我们解释了与健康相关的生活质量结构的层次以及相关的主要维度，包括身体、心理和社会健康。基于HRQoL模型介绍了评估患者报告结局（PROs）的最新方法。此外，还介绍了现代测试理论方法及其应用，其目的是规范和改进PROs的评估（例如计算机自适应测试）。最后，我们介绍了2项主要的国际PRO倡议（PROMIS和欧洲癌症研究与治疗组织生活质量小组），它们在过去几年中对推进患者结局评估产生了影响。
