Hald F, Kristoffersen S E, Hairi J, Hansen M K
Institute of Obstetrics and Gynecology, University of Odense, Denmark.
Acta Obstet Gynecol Scand. 1988;67(1):71-4. doi: 10.3109/00016348809004171.
With the object of examining the diagnostic accuracy of and pain reaction to endocervical curettage (ECC) either by using a new instrument, Vabra mc cervix, or with a conventional 3 mm metal curette, 298 patients with histologically verified cervical intraepithelial neoplasia (CIN) or cytological suspicion have been involved in a consecutive prospective randomized trial. One hundred and forty-eight patients underwent curettage with the Vabra instrument (vabrasio) followed by conventional curettage; 150 underwent the same procedure, but in reverse order. In 114 patients, CIN was ascertained in one or both trials. Vabra mc cervix found normal histology in 23 of these patients (20%), whereas conventional curettage showed normal histology in 58 patients (51%). Quantitatively, Vabra mc cervix extracted significantly more tissue material than did conventional curettage. The pain intensity when using of Vabra mc cervix was less severe. The present study showed diagnostic accuracy of Vabra mc cervix to be 80% (95% confidence limits: 63.38-80.73), compared with 49% (95% confidence limits: 35.17-54.35) when using conventional curettage.
为了检验使用新型器械Vabra mc宫颈刮匙或传统3毫米金属刮匙进行宫颈管搔刮术（ECC）的诊断准确性和疼痛反应，298例经组织学证实为宫颈上皮内瘤变（CIN）或细胞学可疑的患者参与了一项连续的前瞻性随机试验。148例患者先用Vabra器械进行搔刮（Vabra搔刮术），随后进行传统搔刮；150例患者接受相同操作，但顺序相反。在114例患者中，一项或两项试验均确诊为CIN。Vabra mc宫颈刮匙在这些患者中有23例（20%）组织学检查结果正常，而传统搔刮术显示58例患者（51%）组织学检查结果正常。从数量上看，Vabra mc宫颈刮匙获取的组织材料明显多于传统搔刮术。使用Vabra mc宫颈刮匙时疼痛强度较轻。本研究显示，Vabra mc宫颈刮匙的诊断准确性为80%（95%置信区间：63.38 - 80.73），而使用传统搔刮术时为49%（95%置信区间：35.17 - 54.35）。
