Levine R L, Lagreze H L, Dobkin J A, Turski P A
Department of Neurology, William S. Middleton Veterans Administration Hospital, Madison, WI 53705.
Arch Neurol. 1988 Oct;45(10):1074-7. doi: 10.1001/archneur.1988.00520340028006.
A specific form of large subcortical hemispheric infarction on computed tomography was identified in 24 of 2198 (1%) stroke registry patients. Combined with 13 cases from earlier literature reports, a characteristic neurologic picture developed. Severe face plus arm plus leg weakness at onset (76%), corticallike features of aphasia and/or contralateral neglect (68%), and premonitory transient ischemic attacks (24%) were frequent. Twenty-two patients (59%) had large vessel arterial occlusive disease. Eight patients (22%) had primary embolic occlusion in the middle cerebral artery territory. During an average follow-up of 16 months, five patients (14%) suffered recurrent stroke or death. The clinical presentation and prognostic features of this distinct stroke subtype are described.
在2198例卒中登记患者中，有24例（1%）在计算机断层扫描中发现了一种特定形式的大脑半球皮质下大面积梗死。结合早期文献报道的13例病例，形成了一种特征性的神经学表现。发病时严重的面部加手臂加腿部无力（76%）、失语和/或对侧忽视的皮质样特征（68%）以及先兆短暂性脑缺血发作（24%）很常见。22例患者（59%）患有大血管动脉闭塞性疾病。8例患者（22%）在大脑中动脉区域有原发性栓塞性闭塞。在平均16个月的随访期间，5例患者（14%）发生了复发性卒中或死亡。本文描述了这种独特的卒中亚型的临床表现和预后特征。
