Nicolai A, Lazzarino L G, Biasutti E
Divisione Neurologica, Ospedale Civile, Gorizia, Italy.
J Neurol. 1996 Jan;243(1):44-50. doi: 10.1007/BF00878530.
We defined large striatocapsular infarcts as subcortical softenings of more than 20 mm in diameter involving the territories of the lateral and medial groups of lenticulostriate arteries. The aim of this study of 56 patients was to compare the clinical features and risk factors of these infarcts with those of cortical and lacunar infarcts. On the whole, our data suggest that both the clinical features and risk factors of large striatocapsular infarcts are similar to those of cortical infarcts, but significantly different from those of lacunar infarcts. The clinical manifestations of large striatocapsular infarcts with a maximum diameter of less than 50 mm may sometimes resemble those of lacunar infarcts because neuropsychological disorders are less frequent; however, our study indicates that, even in these cases, cardioembolic sources and artery-to-artery embolism are significantly more frequent in large striatocapsular than in lacunar infarcts, thus suggesting a different pathogenesis.
我们将大型纹状体-内囊梗死定义为直径超过20毫米的皮质下软化灶，累及豆纹动脉外侧组和内侧组供血区域。本研究纳入56例患者，旨在比较这些梗死灶与皮质梗死灶和腔隙性梗死灶的临床特征及危险因素。总体而言，我们的数据表明，大型纹状体-内囊梗死灶的临床特征和危险因素与皮质梗死灶相似，但与腔隙性梗死灶显著不同。最大直径小于50毫米的大型纹状体-内囊梗死灶的临床表现有时可能类似于腔隙性梗死灶，因为神经心理障碍较少见；然而，我们的研究表明，即使在这些病例中，大型纹状体-内囊梗死灶中心源性栓塞源和动脉到动脉栓塞的发生率也显著高于腔隙性梗死灶，从而提示其发病机制不同。
