Kamei Naosuke, Adachi Nobuo, Ochi Mitsuo
Department of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Medical Center for Translational & Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.
Regen Ther. 2018 Nov 2;9:116-119. doi: 10.1016/j.reth.2018.10.001. eCollection 2018 Dec.
Magnetic targeting is a cell delivery system using the magnetic labeling of cells and the magnetic field; it has been developed for minimally invasive cell transplantation. Cell transplantation with both minimal invasiveness and high efficacy on tissue repair can be achieved by this system. Magnetic targeting has been applied for the transplantation of bone marrow mesenchymal stem cells, blood CD133-positive cells, neural progenitor cells, and induced pluripotent stem cells, and for the regeneration of bone, cartilage, skeletal muscles, and the spinal cord. It enhances the accumulation and adhesion of locally injected cells, resulting in the improvement of tissue regeneration. It is a promising technique for minimally invasive and effective cell transplantation therapy.
磁靶向是一种利用细胞的磁性标记和磁场的细胞递送系统；它已被开发用于微创细胞移植。通过该系统可以实现对组织修复具有最小侵入性和高效性的细胞移植。磁靶向已应用于骨髓间充质干细胞、血液CD133阳性细胞、神经祖细胞和诱导多能干细胞的移植，以及骨、软骨、骨骼肌和脊髓的再生。它增强了局部注射细胞的积累和粘附，从而改善了组织再生。它是一种用于微创和有效细胞移植治疗的有前途的技术。
