Noguchi T, Marics I, Adelaide J, Raybaud F, Planche J, Batoz M, Auberts C, de Lapeyriere O, Birnbaum D
Unité 119 de l'INSERM, Marseille, France.
Cancer Detect Prev. 1988;12(1-6):383-8.
DNA extracted from fresh solid human melanoma tumors and untreated acute myeloid leukemic cells was used in two assays designed to detect oncogenes, based on the transfection of murine NIH 3T3 fibroblasts followed by selection of transformed cells in low serum concentration or induction of tumors in athymic mice. Ras and non-ras oncogenes were detected.
从新鲜的人类实体黑色素瘤肿瘤和未经处理的急性髓系白血病细胞中提取的DNA,被用于两种旨在检测癌基因的实验中。这两种实验基于将鼠NIH 3T3成纤维细胞进行转染,随后在低血清浓度下选择转化细胞或在无胸腺小鼠中诱导肿瘤形成。检测到了Ras和非Ras癌基因。