College of Animal Science, South China Agricultural University & Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, Guangzhou 510642, PR China.
Guangdong Wen's Foodstuffs Group Co. Ltd., Yunfu 527439, PR China.
Infect Genet Evol. 2019 Mar;68:54-57. doi: 10.1016/j.meegid.2018.12.008. Epub 2018 Dec 6.
Atypical porcine pestivirus (APPV) have been discovered in swine herds from three provinces in China, suggesting a wide distribution in China. This study reports the occurrence of three novel APPV strains in China. They were detected from newborn piglets with clinical signs of congenital tremors (CT) in Guangdong Province, China. The complete genomic sequences of three novel APPV strains exhibited only 80.5%-84.1% nucleotide sequences homology with other APPV reference sequences available in GenBank. Phylogenetic analysis showed that these novel APPV strains formed independent branch from the American, German, Netherlandish, Australian and other Chinese strains. These results will help us better understand the epidemiology and genetic characteristics of APPV in China.
在中国三个省份的猪群中发现了非典型猪瘟病毒（APPV），表明其在中国有广泛的分布。本研究报告了中国三种新型 APPV 毒株的发生情况。它们是从中国广东省出现先天性震颤（CT）临床症状的新生仔猪中检测到的。三种新型 APPV 毒株的完整基因组序列与 GenBank 中其他 APPV 参考序列的核苷酸序列同源性仅为 80.5%-84.1%。系统进化分析表明，这些新型 APPV 毒株与来自美国、德国、荷兰、澳大利亚和其他中国毒株的毒株形成独立分支。这些结果将有助于我们更好地了解中国 APPV 的流行病学和遗传特征。
