Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, the Robert H. Lurie Comprehensive Cancer Center, Northwestern University, and the Center for Healthcare Studies, Institute for Public Health in Medicine, Chicago, Illinois.
Obstet Gynecol. 2019 Jan;133(1):6-12. doi: 10.1097/AOG.0000000000002990.
To estimate the associations among race, route of hysterectomy, and postoperative complications among women undergoing hysterectomy for benign indications.
A cohort study was performed. All patients undergoing hysterectomy for benign indications, recorded in the National Surgical Quality Improvement Program and its targeted hysterectomy file in 2015, were identified. The primary exposure was patient race. The primary outcome was route of hysterectomy and the secondary outcome was postoperative complication. Associations were examined using both bivariable tests and logistic regression.
Of 15,136 women who underwent hysterectomy for benign indications, 75% were white and 25% were black. Black women were more likely to undergo an open hysterectomy than white women (50.1% vs 22.9%; odds ratio [OR] 3.36, 95% CI 3.11-3.64). Black women had larger uteri (median 262 g vs 123 g; 60.7% vs 25.6% with uterus greater than 250 g), more prior pelvic surgery (58.5% vs 53.2%), and higher body mass indices (32.7 vs 30.4). After adjusting for these and other clinical factors, black women remained more likely to undergo an open hysterectomy (adjusted OR 2.02, 95% CI 1.85-2.20). Black women experienced more major complications than white women (4.1% vs 2.3%; P<.001) and more minor complications (11.4% vs 6.7%; OR 1.78, P<.001). Again these disparities persisted with adjustment (major adjusted OR 1.56, 95% CI 1.25-1.95; minor adjusted OR 1.27, 95% CI 1.11-1.47).
Black women undergo a higher proportion of open hysterectomy and experience more major and minor postoperative complications. These differences persisted even after adjusting for confounding medical, surgical, and gynecologic factors.
评估种族、子宫切除术途径与良性指征子宫切除术术后并发症之间的关联。
进行了一项队列研究。2015 年,在全国手术质量改进计划及其针对性子宫切除术档案中,确定了所有因良性指征接受子宫切除术的患者。主要暴露因素是患者种族。主要结局是子宫切除术途径,次要结局是术后并发症。采用双变量检验和逻辑回归分析评估相关性。
在 15136 名因良性指征接受子宫切除术的女性中,75%为白人,25%为黑人。与白人女性相比,黑人女性更有可能接受开放式子宫切除术(50.1%比 22.9%;比值比[OR] 3.36,95%置信区间[CI] 3.11-3.64)。黑人女性的子宫更大(中位数 262 克比 123 克;60.7%比 25.6%的子宫大于 250 克),先前盆腔手术更多(58.5%比 53.2%),体重指数更高(32.7 比 30.4)。在调整这些和其他临床因素后,黑人女性仍然更有可能接受开放式子宫切除术(调整后的 OR 2.02,95%CI 1.85-2.20)。黑人女性经历的主要并发症多于白人女性(4.1%比 2.3%;P<.001),经历的轻微并发症也多于白人女性(11.4%比 6.7%;OR 1.78,P<.001)。这些差异在调整后仍然存在(主要调整后的 OR 1.56,95%CI 1.25-1.95;轻微调整后的 OR 1.27,95%CI 1.11-1.47)。
黑人女性接受开放式子宫切除术的比例更高,经历的主要和次要术后并发症更多。即使在调整混杂的医疗、手术和妇科因素后,这些差异仍然存在。