Yoshida Masayoshi, Ando Shin-Ichi, Kadokami Toshiaki, Narita Sumito, Momii Hidetoshi, Sato Yumi, Kiyokawa Tomoko, Nakao Chikako
Saiseikai Futsukaichi Hospital, Fukuoka, Japan.
J Cardiol Cases. 2010 Dec 14;3(1):e40-e42. doi: 10.1016/j.jccase.2010.10.001. eCollection 2011 Feb.
We report a 30-year-old man with severe obesity hypoventilation syndrome (OHVS) complicated by right-sided heart failure. Polysomnography revealed severe obstructive sleep apnea with apnea-hypopnea index (AHI) 70.4/h and gradual decrease in minimum oxygen saturation (SpO) from 86% before sleep to 36% during sleep. Cardiac output (CO) was suppressed from 3.9 L/min before sleep to 2.5 L/min during sleep. Noninvasive positive pressure ventilation (NPPV) treatment drastically restored CO to the level before sleep, and improved AHI to 9.4/h and minimum SpO to 87%. NPPV may provide rapid and powerful symptom relief in patients with OHVS complicated with right sided heart failure.
我们报告了一名30岁男性，患有严重肥胖低通气综合征（OHVS）并伴有右侧心力衰竭。多导睡眠图显示严重阻塞性睡眠呼吸暂停，呼吸暂停低通气指数（AHI）为70.4次/小时，最低血氧饱和度（SpO）从睡眠前的86%逐渐降至睡眠期间的36%。心输出量（CO）从睡眠前的3.9升/分钟降至睡眠期间的2.5升/分钟。无创正压通气（NPPV）治疗使CO迅速恢复到睡眠前水平，AHI改善至9.4次/小时，最低SpO提高到87%。NPPV可能为合并右侧心力衰竭的OHVS患者提供快速有效的症状缓解。
