Department of Integral Paediatric Dentistry, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain.
PLoS One. 2018 Dec 11;13(12):e0208856. doi: 10.1371/journal.pone.0208856. eCollection 2018.
International guidelines on the prevention of caries recommend sealing of the pits and fissures of the permanent molars. There is no evidence on which type of material is most effective on demineralized enamel.
To evaluate the microleakage of a conventional light-cured, resin-based fissure sealant (LCRBS), GrandiO Seal, and a resin-modified glass ionomer sealant (RMGIS), Vitremer, after application of a fluoride varnish, Bifluorid 12, on demineralized enamel.
80 human third molars were divided into eight groups. The groups combined the three study factors (1) type of enamel (intact or demineralized); (2) enamel non-varnished or varnished with Biflourid12; and (3) type of sealant (GrandiO Seal or Vitremer). The percentage of microleakage after thermocycling was measured using imaging analysis software. The Kruskal-Wallis plus Dunn tests were used to compare differences in microleakage in the different groups.
The lowest microleakage was in the unvarnished groups, and was the same for GrandiO Seal and Vitremer. When varnish was applied, microleakage was greater in demineralized enamel than in intact enamel for both LCRBS and RMGIS.
The application of fluoride varnish on demineralized enamel increases the microleakage of both GrandiO Seal and Vitremer.
国际龋齿预防指南建议对恒磨牙的窝沟进行封闭。对于哪种材料对脱矿釉质最有效,目前尚无证据。
评估氟化物涂料(Bifluorid 12)处理过的脱矿釉质表面应用传统光固化树脂型窝沟封闭剂(LCRBS)GrandiO Seal 和树脂改性玻璃离子体封闭剂(RMGIS)Vitremer 的微渗漏情况。
80 个人类第三磨牙分为 8 组。组间结合 3 个研究因素:(1)釉质类型(完整或脱矿);(2)釉质未涂覆或用 Biflourid12 涂覆;(3)密封剂类型(GrandiO Seal 或 Vitremer)。热循环后使用图像分析软件测量微渗漏百分比。使用 Kruskal-Wallis 加 Dunn 检验比较不同组之间微渗漏的差异。
未涂覆氟化物涂料的组微渗漏最低,GrandiO Seal 和 Vitremer 的微渗漏相同。当涂覆氟化物涂料时,与完整釉质相比,LCRBS 和 RMGIS 在脱矿釉质上的微渗漏更大。
氟化物涂料在脱矿釉质上的应用会增加 GrandiO Seal 和 Vitremer 的微渗漏。