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一名子宫异常出血患者发生原发性宫颈淋巴瘤的病例。

A case of primary cervical lymphoma in a patient with abnormal uterine bleeding.

作者信息

Roberts Maureen E, Cottrill Hope M

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY, 40536, United States.

Department of Gynecologic Oncology, Baptist Health Medical Group, 1740 Nicholasville Rd, Lexington, KY, 40503, United States.

出版信息

Gynecol Oncol Rep. 2018 Nov 2;26:105-107. doi: 10.1016/j.gore.2018.10.014. eCollection 2018 Nov.

DOI:10.1016/j.gore.2018.10.014
PMID:30533475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6260326/
Abstract

Primary lymphoma of the uterine cervix is a rare site of extranodal lymphoma. Many gynecologic oncologists may go their entire career without encountering one. Patients may present with symptoms of abnormal or postmenopausal bleeding, and diagnosis may be challenging as typical office tests such as the pap smear may not detect the abnormal cells. Once a diagnosis is made, management may be debated due to the rarity of the condition and lack of accepted standard treatment. However, most patients respond well to some version of chemotherapy and radiation typically used for standard lymphomas. Prognosis is favorable if the patient is diagnosed early in the disease process.

摘要

子宫颈原发性淋巴瘤是结外淋巴瘤的一个罕见部位。许多妇科肿瘤学家在其整个职业生涯中可能都不会遇到一例。患者可能表现为异常出血或绝经后出血症状,由于典型的门诊检查如巴氏涂片可能无法检测到异常细胞,诊断可能具有挑战性。一旦做出诊断,由于该病罕见且缺乏公认的标准治疗方法,治疗方案可能会存在争议。然而,大多数患者对通常用于标准淋巴瘤的某种化疗和放疗方案反应良好。如果患者在疾病过程中早期被诊断,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/207f4995a442/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/2b752641a3d7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/58c2f9d6068b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/207f4995a442/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/2b752641a3d7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/58c2f9d6068b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2b/6260326/207f4995a442/gr3.jpg

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本文引用的文献

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Gynecol Oncol Rep. 2016 Oct 4;18:29-31. doi: 10.1016/j.gore.2016.10.001. eCollection 2016 Nov.
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A rare presentation of lymphoma of the cervix with cross-sectional imaging correlation.宫颈淋巴瘤的罕见表现及其横断面影像相关性
Case Rep Radiol. 2014;2014:157268. doi: 10.1155/2014/157268. Epub 2014 Apr 17.
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Sonographic features of primary lymphoma of the uterine cervix.子宫颈原发性淋巴瘤的超声特征。
宫腔镜切除术联合辅助放疗:原发性宫颈弥漫性大 B 细胞淋巴瘤的新治疗方法报告。
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Overview of non-Hodgkin's lymphoma.非霍奇金淋巴瘤概述
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Diffuse large B-cell lymphoma of the uterine cervix: a rare case managed novelly.子宫颈弥漫性大B细胞淋巴瘤:1例罕见病例的新治疗方法
J Cancer Res Ther. 2009 Apr-Jun;5(2):140-2. doi: 10.4103/0973-1482.52784.
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Primary follicular lymphoma of the cervix uteri: a review.子宫颈原发性滤泡性淋巴瘤:综述
Ann Hematol. 2007 Sep;86(9):623-30. doi: 10.1007/s00277-007-0328-0. Epub 2007 Jun 22.
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Neoadjuvant combined chemotherapy followed by external whole pelvic irradiation in two cases of primary extranodal non-Hodgkin's lymphoma of the uterine cervix.两例原发性宫颈结外非霍奇金淋巴瘤患者先接受新辅助联合化疗,随后进行全盆腔外照射。
Gynecol Oncol. 2005 Apr;97(1):285-7. doi: 10.1016/j.ygyno.2004.12.018.
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Primary non-Hodgkin's lymphoma of the uterine cervix successfully treated by neoadjuvant chemotherapy: case report.新辅助化疗成功治疗子宫颈原发性非霍奇金淋巴瘤:病例报告
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