Li Wei, He Yan, Xia Lili, Yang Xinghua, Liu Feng, Ma Jingang, Hu Zhiping, Li Yajun, Li Dongxue, Jiang Jiajia, Shan Guangliang, Li Changlong
Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China.
Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
Front Physiol. 2018 Nov 26;9:1574. doi: 10.3389/fphys.2018.01574. eCollection 2018.
Adiposity is one of the important determinants of blood pressure. The aim of this study is to evaluate the association between blood pressure and body composition indices throughout the whole lifespan of healthy adults. This study was from an ongoing cross-sectional survey of the Chinese health wherein data included basic physiological parameters. Partial Pearson correlation analysis was used to assess the correlation between blood pressure and body composition indices. Multiple linear regression analysis was used to assess the association of body mass index, lean mass percent, and visceral fat rating against blood pressure in each age group. In the whole population stratified by gender, while body mass index had the highest r-value of correlation with systolic blood pressure in both males ( = 0.296, < 0.001) and females( = 0.237, < 0.001), and fat mass percent had the highest -value of correlation with diastolic blood pressure in males ( = 0.351, < 0.001) and females( = 0.277, < 0.001), the strength of association with blood pressure were similar across most of the body composition indices. In multiple linear regression analysis, both body mass index and visceral fat rating were positively while lean mass percent was negatively associated with blood pressure in all age groups in both genders, whereas all the association was weaker in the elderly compared to the younger. Maintain the total body fat in a favorable range and appropriately increase the body muscle mass is a strategy to reduce the occurrence of cardiovascular event by decreasing the risk of hypertension through the whole adult life.
肥胖是血压的重要决定因素之一。本研究的目的是评估健康成年人整个生命周期中血压与身体成分指标之间的关联。本研究来自一项正在进行的中国健康横断面调查，其中数据包括基本生理参数。采用偏Pearson相关分析评估血压与身体成分指标之间的相关性。采用多元线性回归分析评估各年龄组体重指数、瘦体重百分比和内脏脂肪等级与血压的关联。在按性别分层的总体人群中，虽然体重指数与收缩压的相关性r值在男性（r = 0.296，P < 0.001）和女性（r = 0.237，P < 0.001）中均最高，脂肪量百分比与舒张压的相关性r值在男性（r = 0.351，P < 0.001）和女性（r = 0.277，P < 0.001）中均最高，但大多数身体成分指标与血压的关联强度相似。在多元线性回归分析中，体重指数和内脏脂肪等级在所有年龄组的男女中均与血压呈正相关，而瘦体重百分比与血压呈负相关，然而与年轻人相比，老年人的所有关联都较弱。在整个成年期，将全身脂肪维持在适宜范围内并适当增加身体肌肉量是一种通过降低高血压风险来减少心血管事件发生的策略。
