Haiun Mathieu, Barbara Hersant, Durazzo Adrien, Sid-Ahmed-Mezi Mounia, Meningaud Jean-Paul
Service of Plastic, Reconstructive and Aesthetic Surgery, and Maxillo-facial Surgery, Henri Mondor's Hospital, Créteil Cedex.
Plast Reconstr Surg Glob Open. 2018 Oct 4;6(10):e1907. doi: 10.1097/GOX.0000000000001907. eCollection 2018 Oct.
Massive weight loss following bariatric surgery has a major functional and aesthetic impact on patients. Many patients are nonetheless reluctant to undergo plastic surgery in connection with their former obesity because they fear potentially large scars, even though such scars are not visible (ie, they are covered by undergarments).
The aim of this study was to evaluate the quality of wound healing in patients receiving Celergen supplementation following abdominoplasty, compared with a control group. The hypothesis was that supplementation would speed up wound healing and improve scar quality.
We conducted a prospective, monocentric, controlled study of patients undergoing abdominoplasty. A group of patients received Celergen, a food supplement, for 3 months and were monitored for 1 year after their surgery.
Of 33 patients who underwent abdominoplasty, 25 received Celergen supplements. There was no significant difference between the 2 groups. The mean time to wound healing was significantly better in the group receiving supplementation compared with the control group [respectively, 24.6 ± 9.31 days and 34 ± 13.48 days ( = 0.03)]. The Patient and Observer Scar Assessment Scale (POSAS) observer score was significantly better at 1 year in the group receiving supplementation compared with the control group [12.68 ± 6.6 and 17.38 ± 5.24 ( = 0.01), respectively]. There was no significant difference in the total POSAS score at 1 year ( = 0.166).
Celergen supplementation significantly improved the time to healing and the POSAS observer score at 1 year for patients undergoing abdominoplasty.
减肥手术后的大量体重减轻对患者的功能和美观有重大影响。然而,许多患者尽管担心可能会留下大疤痕,但仍不愿因先前的肥胖问题接受整形手术,即便这些疤痕并不明显(即被内衣覆盖)。
本研究旨在评估腹部整形术后补充Celergen的患者与对照组相比的伤口愈合质量。假设是补充Celergen会加速伤口愈合并改善疤痕质量。
我们对接受腹部整形手术的患者进行了一项前瞻性、单中心、对照研究。一组患者接受了3个月的Celergen(一种食品补充剂),并在术后接受了1年的监测。
在33例接受腹部整形手术的患者中,25例接受了Celergen补充剂。两组之间无显著差异。与对照组相比,接受补充剂的组伤口愈合的平均时间明显更短[分别为24.6±9.31天和34±13.48天(P = 0.03)]。与对照组相比,接受补充剂的组在1年时患者和观察者疤痕评估量表(POSAS)的观察者评分明显更好[分别为12.68±6.6和17.38±5.24(P = 0.01)]。1年时POSAS总分无显著差异(P = 0.166)。
对于接受腹部整形手术的患者,补充Celergen显著缩短了愈合时间,并提高了1年时的POSAS观察者评分。