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人脑脊液中淋巴细胞的表面标志物。携带IgG Fc段受体的T淋巴细胞占优势。

Surface markers on lymphocytes from human cerebrospinal fluid. Predominance of T lymphocytes bearing receptors for the Fc segment of IgG.

作者信息

Manconi P E, Zaccheo D, Bugiani O, Fadda M F, Cadoni A, Marrosu M G, Cianchetti C, Grifoni V

出版信息

Eur Neurol. 1978;17(2):87-91. doi: 10.1159/000114929.

DOI:10.1159/000114929
PMID:305355
Abstract

Surface markers of cerebrospinal fluid (CSF) cells have been studied in comparison with those of peripheral blood lymphocytes. The great majority (about 95%) of CSF cells bear surface markers of thymus-dependent lymphocytes (E rosettes with uncoated sheep red blood cells), while being devoid of bone-marrow derived cell markers (EAC rosettes with complement-coated red blood cells). In contrast with lymphocytes from peripheral blood, CSF cells form predominantly 'early' and 'sphere'-shaped E rosettes, and bear receptors for the complement-fixing segment of immunoglobulins G. Treatment with concentrated CSF does not affect rosette forming ability of peripheral blood lymphocytes.

摘要

已经对脑脊液(CSF)细胞的表面标志物与外周血淋巴细胞的表面标志物进行了比较研究。绝大多数(约95%)的脑脊液细胞带有胸腺依赖性淋巴细胞的表面标志物(与未包被的绵羊红细胞形成E花环),而缺乏骨髓来源细胞的标志物(与补体包被的红细胞形成EAC花环)。与外周血淋巴细胞相比,脑脊液细胞主要形成“早期”和“球形”E花环,并带有免疫球蛋白G补体固定片段的受体。用浓缩脑脊液处理并不影响外周血淋巴细胞形成花环的能力。

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1
Surface markers on lymphocytes from human cerebrospinal fluid. Predominance of T lymphocytes bearing receptors for the Fc segment of IgG.人脑脊液中淋巴细胞的表面标志物。携带IgG Fc段受体的T淋巴细胞占优势。
Eur Neurol. 1978;17(2):87-91. doi: 10.1159/000114929.
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T lymphocytes bearing receptors for Fc of IgG in guinea pig peritoneal fluid. A model for human extrahaematic fluids.豚鼠腹膜液中带有IgG Fc受体的T淋巴细胞。人类血液外液的一个模型。
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Allogeneic lymphocyte-dependent antibodies (LDA). Specificity of Fc receptors.同种异体淋巴细胞依赖性抗体(LDA)。Fc受体的特异性。
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T lymphocytes in cerebrospinal fluid from patients with neurological diseases.患有神经系统疾病患者脑脊液中的T淋巴细胞。
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