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患有神经系统疾病患者脑脊液中的T淋巴细胞。

T lymphocytes in cerebrospinal fluid from patients with neurological diseases.

作者信息

Naess A

出版信息

Eur Neurol. 1979;18(3):183-8. doi: 10.1159/000115074.

DOI:10.1159/000115074
PMID:314380
Abstract

T lymphocytes were determined according to their ability to form rosettes with sheep erythrocytes, in cerebrospinal fluid (CSF) from 120 patients, and in peripheral blood from 59 patients. Normal CSF contained 74.9 +/- 9.6% T lymphocytes. Increased T lymphocyte percentage was found in CSF from patients with active multiple sclerosis (MS), and Guillain-Barré syndrome, as well as the 2 patients with retrobulbar neuritis and the 1 with subacute sclerosing panencephalitis. Patients with stable MS showed no significant change in CSF T lymphocyte percentage. CSF from patients with viral meningo-encephalitis or meningo-radiculitis had a decreased T lymphocyte percentage. This decrease was also found in the 2 patients with malignant disease and the 2 with presenile dementia. An exceptionally low CSF T cell count (5%) was found in 1 patient with cerebellar ataxia.

摘要

根据T淋巴细胞与绵羊红细胞形成玫瑰花结的能力,对120例患者的脑脊液(CSF)和59例患者的外周血进行了检测。正常脑脊液中T淋巴细胞含量为74.9±9.6%。在活动性多发性硬化症(MS)、格林-巴利综合征患者的脑脊液中,以及2例球后视神经炎患者和1例亚急性硬化性全脑炎患者的脑脊液中,T淋巴细胞百分比升高。病情稳定的MS患者脑脊液中T淋巴细胞百分比无显著变化。病毒性脑膜脑炎或脑膜神经根炎患者的脑脊液中T淋巴细胞百分比降低。在2例恶性疾病患者和2例早老性痴呆患者中也发现了这种降低。1例小脑共济失调患者的脑脊液T细胞计数异常低(5%)。

相似文献

1
T lymphocytes in cerebrospinal fluid from patients with neurological diseases.患有神经系统疾病患者脑脊液中的T淋巴细胞。
Eur Neurol. 1979;18(3):183-8. doi: 10.1159/000115074.
2
T lymphocytes in peripheral blood from patients with neurological diseases.患有神经系统疾病患者外周血中的T淋巴细胞。
Acta Neurol Scand. 1978 Nov;58(5):272-9. doi: 10.1111/j.1600-0404.1978.tb02887.x.
3
Surface markers on lymphocytes from human cerebrospinal fluid. Predominance of T lymphocytes bearing receptors for the Fc segment of IgG.人脑脊液中淋巴细胞的表面标志物。携带IgG Fc段受体的T淋巴细胞占优势。
Eur Neurol. 1978;17(2):87-91. doi: 10.1159/000114929.
4
Characterization of active T cells in CSF and blood in multiple sclerosis patients and controls.多发性硬化症患者及对照者脑脊液和血液中活性T细胞的特征分析。
Scand J Immunol. 1980;12(2):99-108. doi: 10.1111/j.1365-3083.1980.tb00046.x.
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Multiple sclerosis. T lymphocytes in cerebrospinal fluid and blood.
Eur Neurol. 1978;17(2):61-6. doi: 10.1159/000114925.
6
T-lymphocyte subpopulation levels and immunoglobulin changes in the cerebrospinal fluid of patients with neurologic disorders.神经系统疾病患者脑脊液中T淋巴细胞亚群水平及免疫球蛋白变化
Ann N Y Acad Sci. 1987;496:691-6. doi: 10.1111/j.1749-6632.1987.tb35831.x.
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B and T lymphocytes in cerebrospinal fluid and blood in multiple sclerosis, optic neuritis and mumps meningitis.多发性硬化症、视神经炎及腮腺炎脑膜炎患者脑脊液和血液中的B淋巴细胞及T淋巴细胞
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J Neurol. 1981;225(1):63-5. doi: 10.1007/BF00313463.