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杓状软骨硬化与声门型喉癌:一项临床病理研究。

Sclerosis of the arytenoid cartilage and glottic carcinoma: A clinical-pathological study.

机构信息

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy.

Pathology Section, Conegliano Hospital, Treviso, Italy.

出版信息

Head Neck. 2019 Jan;41(1):72-78. doi: 10.1002/hed.25372. Epub 2018 Dec 7.

DOI:10.1002/hed.25372
PMID:30536660
Abstract

BACKGROUND

Given the relevance of any tumor invasion of the arytenoid cartilage or crico-arytenoid unit to the planning open partial horizontal laryngectomy (OPHL) for laryngeal squamous cell carcinoma (LSCC), it is important to have a reliable radiological test to assess impairments of these structures.

METHODS

We retrospectively compared the endoscopic, radiological, and pathological findings in patients with glottic LSCC who underwent OPHL.

RESULTS

The endoscopic finding of a reduced (impaired or absent) vocal cord motility proved more sensitive, with better positive and negative predictive values, but less specific than the radiological finding of complete arytenoid sclerosis in detecting histologically assessable infiltration of the arytenoid cartilage.

CONCLUSIONS

Endoscopy retains a key role in the preoperative workup for glottic LSCC. CT evidence of complete sclerosis of the arytenoid cartilage is related to a dangerous contiguity of the tumor to the cartilage.

摘要

背景

鉴于声门旁软骨或环杓关节单位的任何肿瘤侵犯与喉鳞状细胞癌(LSCC)开放式部分水平喉切除术(OPHL)的规划相关,因此,有必要进行可靠的影像学检查来评估这些结构的损伤。

方法

我们回顾性比较了接受 OPHL 的声门型 LSCC 患者的内镜、影像学和病理学检查结果。

结果

与影像学上发现完全杓状软骨硬化相比,内镜下发现声带运动受限(受损或缺失)在检测声门旁软骨的组织学可评估浸润方面具有更高的敏感性、更好的阳性和阴性预测值,但特异性较低。

结论

内镜检查在声门型 LSCC 的术前评估中仍然具有重要作用。CT 证据显示完全性杓状软骨硬化与肿瘤与软骨的危险毗邻有关。

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Head Neck. 2019 Jan;41(1):72-78. doi: 10.1002/hed.25372. Epub 2018 Dec 7.
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