Muñoz A, Ramos A, Ferrando J, Gómez B, Escudero L, Relea F, García-Prats D, Rodríguez F
Department of Radiology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Radiology. 1993 Nov;189(2):433-7. doi: 10.1148/radiology.189.2.8210372.
To assess the significance of sclerotic-appearing cricoid and arytenoid cartilage with computed tomography (CT) in patients with laryngeal carcinoma.
CT scans obtained in 75 patients with laryngeal carcinoma were prospectively studied; laryngeal CT studies obtained in 50 patients without laryngeal carcinoma were retrospectively reviewed.
Twenty-four of the 75 patients (32%) with laryngeal carcinoma had sclerotic cartilage. Evaluation of pathologic specimens obtained in 12 of these 24 patients showed 11 cases of sclerotic arytenoid cartilage and two cases of sclerotic cricoid cartilage. Tumor infiltration was demonstrated in six of these cases but not in the seven others. In 11 of the 12 cases with pathologic proof, however, tumor was adjacent to the perichondrium. In the 12 cases without pathologic proof, the proportion was similar. The positive predictive value of this sign for cartilaginous invasion was 46%.
Although it is not a reliable sign of cartilaginous invasion, sclerotic-appearing cricoid and arytenoid cartilage in patients with laryngeal carcinoma is predictive of the tumor to this cartilage.
通过计算机断层扫描（CT）评估喉癌患者中出现硬化表现的环状软骨和杓状软骨的意义。
对75例喉癌患者的CT扫描进行前瞻性研究；对50例无喉癌患者的喉部CT研究进行回顾性分析。
75例喉癌患者中有24例（32%）出现软骨硬化。对这24例患者中的12例获取的病理标本进行评估，结果显示11例为杓状软骨硬化，2例为环状软骨硬化。其中6例存在肿瘤浸润，另外7例未发现肿瘤浸润。然而，在12例有病理证据的病例中，有11例肿瘤紧邻软骨膜。在12例无病理证据的病例中，该比例相似。此征象对软骨侵犯的阳性预测值为46%。
尽管它不是软骨侵犯的可靠征象，但喉癌患者中出现硬化表现的环状软骨和杓状软骨提示肿瘤侵犯该软骨。
