Etheridge M E, Yolken R H, Vonderfecht S L
Division of Comparative Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
J Clin Microbiol. 1988 Sep;26(9):1741-4. doi: 10.1128/jcm.26.9.1741-1744.1988.
A Lancefield group D enteric streptococcus was isolated from diarrheic suckling rats that had been inoculated orally with stool from a diarrheic human. After oral administration of the organism to other suckling rats, diarrhea was reproduced, and the enteric streptococcus was reisolated. The brush border of small intestinal villi in affected animals was coated with numerous adherent gram-positive cocci. The organism was identified as Enterococcus hirae by a battery of biochemical tests. These and previous studies indicate that certain enterococci should be considered as etiologic agents of diarrheal disease in neonatal animals.
从经口接种腹泻人类粪便的腹泻乳鼠中分离出一株兰斯菲尔德D群肠道链球菌。将该菌口服接种给其他乳鼠后，再次引发腹泻，且再次分离出该肠道链球菌。患病动物小肠绒毛的刷状缘上覆盖有大量黏附的革兰氏阳性球菌。通过一系列生化试验，该菌被鉴定为海氏肠球菌。这些研究以及之前的研究表明，某些肠球菌应被视为新生动物腹泻病的病原体。
