Liu Yinan, Robinson Douglas
Departments of Cell Biology and Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA.
F1000Res. 2018 Nov 26;7. doi: 10.12688/f1000research.16502.1. eCollection 2018.
During cytokinesis, the cell employs various molecular machineries to separate into two daughters. Many signaling pathways are required to ensure temporal and spatial coordination of the molecular and mechanical events. Cells can also coordinate division with neighboring cells to maintain tissue integrity and flexibility. In this review, we focus on recent advances in the understanding of the molecular underpinnings of cytokinesis.
在胞质分裂过程中,细胞利用各种分子机制分裂为两个子细胞。需要许多信号通路来确保分子和机械事件的时间和空间协调。细胞还可以与相邻细胞协调分裂,以维持组织的完整性和柔韧性。在这篇综述中,我们重点关注对胞质分裂分子基础理解的最新进展。