Bays H E, Pfeifer M A
Department of Medicine, University of Louisville School of Medicine, Kentucky.
Med Clin North Am. 1988 Nov;72(6):1439-64. doi: 10.1016/s0025-7125(16)30716-7.
Diabetic neuropathy is a common complication of diabetes mellitus with significant morbidity and mortality. Hyperglycemia with its secondary metabolic, vascular, and enzymatic consequences is most likely to be the predominant cause. The clinical manifestations includes a wide range of somatic and autonomic syndromes. Painful diabetic neuropathy may require symptomatic treatment. The precise role of therapies such as continuous subcutaneous insulin therapy and aldose reductase inhibitors remains to be clarified.
糖尿病性神经病变是糖尿病常见的并发症，具有较高的发病率和死亡率。高血糖及其继发的代谢、血管和酶学后果很可能是主要病因。临床表现包括广泛的躯体和自主神经综合征。疼痛性糖尿病性神经病变可能需要对症治疗。持续皮下胰岛素治疗和醛糖还原酶抑制剂等治疗方法的确切作用仍有待阐明。
