Darling T N, Balber A E, Blum J J
Department of Physiology, Duke University Medical Center, Durham, NC 27710.
Mol Biochem Parasitol. 1988 Sep;30(3):253-7. doi: 10.1016/0166-6851(88)90094-1.
Leishmania braziliensis panamensis, L. donovani, L. major, and L. mexicana amazonensis promastigotes, Trypanosoma lewisi bloodstream forms, and T. brucei gambiense procyclic forms were incubated with glucose as sole carbon source. All species consumed glucose more rapidly under aerobic than anaerobic conditions. All produced glycerol under anaerobic conditions, though the rate of glycerol production by T. lewisi was markedly lower than that by the other species. The four Leishmania species produced D-lactate, but not L-lactate, whereas T. b. gambiense procyclic forms produced L-lactate, but not D-lactate, and T. lewisi produced both isomers.
将巴西利什曼原虫巴拿马亚种、杜氏利什曼原虫、硕大利什曼原虫和亚马逊利什曼原虫墨西哥亚种的前鞭毛体、路氏锥虫的血流形式以及布氏冈比亚锥虫的前循环形式，以葡萄糖作为唯一碳源进行培养。在有氧条件下，所有物种消耗葡萄糖的速度都比无氧条件下更快。在无氧条件下，所有物种都会产生甘油，不过路氏锥虫产生甘油的速度明显低于其他物种。四种利什曼原虫物种产生D-乳酸，但不产生L-乳酸，而布氏冈比亚锥虫前循环形式产生L-乳酸，但不产生D-乳酸，路氏锥虫则产生两种异构体。
