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在感染牙槽窝中即刻种植时，富血小板生长因子两次使用与一次使用的稳定性比较。

Comparison of stability with two-time use of platelet-rich growth factor versus one-time use of platelet-rich growth factor in immediate placement of dental implant in infected socket.

作者信息

Pal Uma Shankar, Daga Dipti, Singh R K, Kumar Lakshya, Singh Mayank

机构信息

Department of Oral and Maxillofacial Surgery, Crowns and Bridges, King George's Medical University, Lucknow, Uttar Pradesh, India.

Department of Prosthodontics, Crowns and Bridges, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Natl J Maxillofac Surg. 2018 Jul-Dec;9(2):209-214. doi: 10.4103/njms.NJMS_1_18.

DOI:10.4103/njms.NJMS_1_18
PMID:30546237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6251289/
Abstract

PURPOSE

The aim is to evaluate the outcome and compare the stability with two-time use of platelet-rich growth factor (PRGF) versus one-time use of PRGF in immediate placement of dental implant in infected socket.

MATERIALS AND METHODS

This study comprised placement of immediate implant in infected sockets in 100 patients with two-time use of PRGF (Group B) versus one-time use of PRGF (Group A). Proper administration of antibiotics, careful debridement of the socket, and meticulous suturing were done in every case. In Group A, it was placed at the time of immediate implant placement. In Group B, it was placed twice: at the time of placement of implant and 1 month after placement of implant. Clinical assessment of pain and swelling was done. Stability was assessed by radiofrequency analyzer immediately after placement and at follow-up of 2 months and 3 months.

RESULTS

The stability of implants with two-time placement of PRGF was more than that with one-time placement of dental implant. All except 14 implants osseointegrated in this study. There was significant decrease of pain and swelling in both the groups from day 1 to week 1 and was nil by 12 weeks.

CONCLUSION

It can be concluded that placement of immediate implant in infected socket with two-time use of PRGF is an effective and better alternative for rehabilitation. However, more studies with longer follow-up and large number of patients are needed to confirm the results of this study.

摘要

目的

旨在评估在感染牙槽窝即刻种植中两次使用富血小板生长因子（PRGF）与一次使用PRGF的效果及稳定性，并进行比较。

材料与方法

本研究纳入100例患者，在感染牙槽窝中即刻种植，其中一组两次使用PRGF（B组），另一组一次使用PRGF（A组）。每组病例均合理使用抗生素、仔细清创牙槽窝并精细缝合。A组在即刻种植时放置PRGF；B组放置两次：种植时及种植后1个月。对疼痛和肿胀进行临床评估。在种植体植入后即刻以及2个月和3个月随访时，通过射频分析仪评估稳定性。

结果

两次放置PRGF的种植体稳定性高于一次放置PRGF的种植体。本研究中除14枚种植体外，其余均实现骨整合。两组从第1天到第1周疼痛和肿胀均显著减轻，至12周时消失。

结论

可以得出结论，在感染牙槽窝即刻种植时两次使用PRGF是一种有效且更好的修复替代方法。然而，需要更多随访时间更长、患者数量更多的研究来证实本研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/c5b0f4b7b644/NJMS-9-209-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/af4a8396f262/NJMS-9-209-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/406905ee0680/NJMS-9-209-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/e47337578a3c/NJMS-9-209-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/675e162e7c28/NJMS-9-209-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/7fff43cdcd3e/NJMS-9-209-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/634eac2c8252/NJMS-9-209-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/edc533d6f831/NJMS-9-209-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/b94b7bbfcbac/NJMS-9-209-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/8ac4866bde6a/NJMS-9-209-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/c5b0f4b7b644/NJMS-9-209-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/af4a8396f262/NJMS-9-209-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/406905ee0680/NJMS-9-209-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/e47337578a3c/NJMS-9-209-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/675e162e7c28/NJMS-9-209-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/7fff43cdcd3e/NJMS-9-209-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/634eac2c8252/NJMS-9-209-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/edc533d6f831/NJMS-9-209-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/b94b7bbfcbac/NJMS-9-209-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/8ac4866bde6a/NJMS-9-209-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9d/6251289/c5b0f4b7b644/NJMS-9-209-g010.jpg

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