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使用碘卡明葡胺进行腰椎脊髓造影后发生的椎管内蛛网膜炎和脑积水。

Intraspinal arachnoiditis and hydrocephalus after lumbar myelography using methylglucamine iocarmate.

作者信息

Jensen T S, Hein O

出版信息

J Neurol Neurosurg Psychiatry. 1978 Feb;41(2):108-12. doi: 10.1136/jnnp.41.2.108.

DOI:10.1136/jnnp.41.2.108
PMID:305466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC492976/
Abstract

A 35 year old woman developed a severe meningeal reaction after lumbar myelography using the water-soluble contrast medium methylglucamine iocarmate. Three months after myelography the findings were a transverse spinal cord syndrome corresponding to the middle thoracic segments resulting from well developed leptomeningeal adhesions. This was combined with a noncommunicating hydrocephalus, probably the result of leptomeningeal fibrosis in the posterior fossa. After treatment with a ventriculoatrial shunt the patient is almost free of symptoms. A possible pathogenetic relationship between the contrast medium, the chronic leptomeningeal changes, and the symptoms of our patient is discussed on the basis of the literature.

摘要

一名35岁女性在使用水溶性造影剂碘卡明葡胺进行腰椎脊髓造影后出现严重的脑膜反应。脊髓造影三个月后,发现因软脑膜粘连严重而导致相当于胸中段的横贯性脊髓综合征。同时伴有非交通性脑积水,可能是后颅窝软脑膜纤维化的结果。在进行脑室心房分流术后,患者几乎无症状。根据文献讨论了造影剂、慢性软脑膜改变与该患者症状之间可能的发病机制关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/92e37c60af59/jnnpsyc00140-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/729ec7a0938b/jnnpsyc00140-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/93a75dfb4de2/jnnpsyc00140-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/92e37c60af59/jnnpsyc00140-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/729ec7a0938b/jnnpsyc00140-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/93a75dfb4de2/jnnpsyc00140-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6130/492976/92e37c60af59/jnnpsyc00140-0015-a.jpg

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Intraspinal arachnoiditis and hydrocephalus after lumbar myelography using methylglucamine iocarmate.使用碘卡明葡胺进行腰椎脊髓造影后发生的椎管内蛛网膜炎和脑积水。
J Neurol Neurosurg Psychiatry. 1978 Feb;41(2):108-12. doi: 10.1136/jnnp.41.2.108.
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引用本文的文献

1
The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).软脑膜作为中枢神经系统正常发育和功能的关键器官:首例患者和公众参与的蛛网膜炎(慢性脑膜炎)的系统评价。
PLoS One. 2022 Sep 30;17(9):e0274634. doi: 10.1371/journal.pone.0274634. eCollection 2022.

本文引用的文献

1
Complications of pantopaque myelography. Case report and review.碘苯酯脊髓造影术的并发症。病例报告及文献复习。
J Neurosurg. 1962 Apr;19:302-11. doi: 10.3171/jns.1962.19.4.0302.
2
Acute meningeal reaction following Pantopaque myelography.碘苯酯脊髓造影术后的急性脑膜反应。
J Neurosurg. 1971 Mar;34(3):396-404. doi: 10.3171/jns.1971.34.3.0396.
3
[Experimental studies on the elimination and neurotoxicity of a new water soluble contrast medium for lumbosacral myelography].[一种新型水溶性造影剂用于腰骶部脊髓造影的排泄及神经毒性实验研究]
Radiologe. 1972 Feb;12(2):66-8.
4
Adhesive arachnoiditis after lumbar myelography with meglumine iothalamate (Conray).使用碘他拉葡胺(康瑞)进行腰椎脊髓造影后发生的粘连性蛛网膜炎。
Acta Radiol Diagn (Stockh). 1972 Jan;12(1):17-24. doi: 10.1177/028418517201200104.
5
Side effects of Conray Meglumin 282 and Dimer-X in lumbar myelography.泛影葡胺282和双聚体X用于腰椎脊髓造影的副作用。
Acta Radiol Diagn (Stockh). 1972 Jan;12(1):12-6. doi: 10.1177/028418517201200103.
6
Side effects of water-soluble contrast media in lumbar myelography.水溶性造影剂在腰椎脊髓造影中的副作用。
Acta Radiol Diagn (Stockh). 1973 Nov;14(6):647-56. doi: 10.1177/028418517301400603.
7
Long term side effects after myelography with watersoluble contrast media: Conturex, Conray Meglumin 282 and Dimer-X.水溶性造影剂脊髓造影后的长期副作用:康锐克斯、康瑞( meglumine 282)和二聚体-X。
Neuroradiology. 1973 Dec;6(4):206-11. doi: 10.1007/BF00335325.
8
Hyperosmolality of the cerebrospinal fluid as a cause of adhesive arachnoiditis in lumbar myelography.脑脊液高渗作为腰椎脊髓造影中粘连性蛛网膜炎的一个病因。
Acta Radiol Diagn (Stockh). 1974 Nov;15(6):619-29. doi: 10.1177/028418517401500604.
9
Visual loss: a rare complication following oil myelography. Case report and review of the literature.视力丧失:油剂脊髓造影术后一种罕见的并发症。病例报告及文献综述
Neuroradiology. 1974 Jul 29;7(5):287-90. doi: 10.1007/BF00344249.
10
Leptomeningeal changes following lumbar myelography with water-soluble contrast media (meglumine iothalamate and methiodal sodium).水溶性造影剂(碘他拉葡胺和甲泛葡胺)腰椎脊髓造影后的软脑膜改变。
Neuroradiology. 1973 Apr;5(2):70-6. doi: 10.1007/BF00337486.