Shi Bei, Wei Wenjuan, Qin Xin, Zhao Fangkun, Duan Yucen, Sun Weinan, Li Da, Cao Yu
Department of Physiology, College of Life Science, China Medical University, Shenyang 110122, PR China.
Functional Laboratory Center, College of Basic Medical Science, China Medical University, Shenyang 110122, PR China.
Regen Med. 2019 Jan;14(1):33-48. doi: 10.2217/rme-2018-0117. Epub 2018 Dec 14.
To investigate the theme trends and knowledge structure of adipose-derived stem cells (ADSCs) related literatures by using bibliometric analysis.
MATERIALS & METHODS: Co-word analysis, strategic diagram and social network analysis were employed.
In line with strategic diagrams, ADSC differentiation and transplantation as main undeveloped themes in 2003-2007 were partially replaced by regeneration medicine and ADSCs for myocardial infarction in 2008 to 2012, and then partially replaced by miRNAs in ADSC genetics and nerve regeneration in 2013 to 2017. Based on social network analysis, regenerative medicine/methods, myocardial infarction/therapy, as well as miRNAs/genetics, and nerve regeneration/physiology were considered the emerging hot spots in 2008 to 2012 and 2013 to 2017.
The undeveloped themes and emerging hot spots could be considered as new research topics.
通过文献计量分析研究脂肪来源干细胞（ADSCs）相关文献的主题趋势和知识结构。
采用共词分析、战略图和社会网络分析。
根据战略图，2003 - 2007年作为主要未开发主题的ADSC分化和移植在2008至2012年部分被再生医学和用于心肌梗死的ADSCs所取代，然后在2013至2017年部分被ADSC遗传学中的miRNAs和神经再生所取代。基于社会网络分析，再生医学/方法、心肌梗死/治疗以及miRNAs/遗传学和神经再生/生理学在2008至2012年和2013至2017年被视为新兴热点。
未开发主题和新兴热点可被视为新的研究课题。
