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什么是早产儿血流动力学显著的动脉导管未闭?

What is a hemodynamically significant PDA in preterm infants?

作者信息

Shepherd Jennifer L, Noori Shahab

机构信息

Fetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California.

出版信息

Congenit Heart Dis. 2019 Jan;14(1):21-26. doi: 10.1111/chd.12727. Epub 2018 Dec 12.

DOI:10.1111/chd.12727
PMID:30548469
Abstract

OBJECTIVE

There is no consensus on the definition of a hemodynamically significant patent ductus arteriosus (hsPDA). In this review article, our objective is to discuss the main variables that one should consider when determining the hemodynamic significance of a PDA.

RESULTS

We describe the various approaches that have been utilized over time to define an hsPDA and discuss the strengths and weaknesses of each echocardiographic index. Finally, we propose a comprehensive and individualized approach in determining the hemodynamic significance of the PDA.

CONCLUSION

There are several PDA-related clinical, echocardiographic, and other objective variables to take into consideration when defining an hsPDA. However, vulnerability based on gestational or chronological age is an important contributor as well.

摘要

目的

关于血流动力学显著的动脉导管未闭(hsPDA)的定义尚无共识。在这篇综述文章中,我们的目的是讨论在确定动脉导管未闭的血流动力学意义时应考虑的主要变量。

结果

我们描述了随着时间推移用于定义hsPDA的各种方法,并讨论了每个超声心动图指标的优缺点。最后,我们提出了一种全面且个体化的方法来确定动脉导管未闭的血流动力学意义。

结论

在定义hsPDA时,有几个与动脉导管未闭相关的临床、超声心动图及其他客观变量需要考虑。然而,基于胎龄或实际年龄的易感性也是一个重要因素。

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1
What is a hemodynamically significant PDA in preterm infants?什么是早产儿血流动力学显著的动脉导管未闭?
Congenit Heart Dis. 2019 Jan;14(1):21-26. doi: 10.1111/chd.12727. Epub 2018 Dec 12.
2
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