Chiba Koji, Fujisawa Masato
Nihon Rinsho. 2017 Apr;75(4):588-592.
Testosterone deficiency has recently drawn wide attention due to the high prevalence of hypo-gonadal symptoms in the aging male population. A number of studies have reported the beneficial effects of testosterone replacement therapy for men with late-onset hypogonadism (LOH) syndrome. Based on the study evaluating the age distribution of serum testosterone concentration, serum free testosterone less than 8.5 pg/mL is considered as a good indica- tion for testosterone replacement therapy among the Japanese population. However, at present, testosterone enanthate is the only drug that is covered by health insurance in Japan. Further studies are needed to establish more suitable treatment in men with LOH syndrome among Japanese population.
由于老年男性人群性腺功能减退症状的高患病率，睾酮缺乏最近引起了广泛关注。许多研究报告了睾酮替代疗法对迟发性性腺功能减退（LOH）综合征男性的有益作用。根据一项评估血清睾酮浓度年龄分布的研究，血清游离睾酮低于8.5 pg/mL被认为是日本人群中睾酮替代疗法的良好指征。然而，目前庚酸睾酮是日本医疗保险覆盖的唯一药物。需要进一步研究，以便在日本人群中为LOH综合征男性建立更合适的治疗方法。
