Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Laboratory of Dentistry and Applied Materials (LDAM), Research and Development Institute (IP&D), Universidade do Vale do Paraíba, Univap, São José dos Campos, São Paulo, Brazil.
Head Neck. 2019 Jan;41(1):162-169. doi: 10.1002/hed.25493. Epub 2018 Dec 15.
The radiotherapy can directly affect the bond strength of the adhesive materials, interfering in the prognosis of restorative treatments, which may be caused by chemical changes in dentin structure.
Twenty inferior homologues premolars were distributed in 2 groups (in vitro study) (n = 10): nonirradiated and irradiated. The specimens were submitted to the analysis of phosphate (ν PO ;ν PO ;ν PO ), carbonate (ν CO ), amide I, CH , amide III, and amide I/III ratio by confocal Raman spectroscopy. Data were submitted to statistical analysis (T test, P < .05).
In intracanal dentin, the irradiated group had lower ν PO values (1.23 ± 0.06) compared to nonirradiated group (1.40 ± 0.18) (P < .05), with no difference for ν PO and ν PO peaks (P > .05). The irradiated (1.56 ± 0.06) had lower carbonate, amide III (1.05 ± 0.19), and amide I/III ratio values (0.19 ± 0.06) compared to nonirradiated group (1.42 ± 0.10, 1.28 ± 0.24, and 0.31 ± 0.10, respectively) (P < .05). For medium dentin irradiated group (1.30 ± 0.12) had lower phosphate values compared to nonirradiated group (1.48 ± 0.22) (P < .05). In cementum, there was no statistical difference between the groups.
The radiotherapy was able to cause changes in ν PO , carbonate, and amide III peaks of root dentin.
放射治疗会直接影响黏结材料的黏结强度，从而影响修复治疗的预后，这可能是牙本质结构的化学变化所致。
将 20 颗下恒前磨牙分为 2 组（体外研究）（n=10）：未照射组和照射组。对标本进行磷酸盐（ν PO ；ν PO ；ν PO ）、碳酸盐（ν CO ）、酰胺 I、CH 、酰胺 III 和酰胺 I/III 比值的分析，采用共焦拉曼光谱法。数据采用统计学分析（T 检验，P<0.05）。
在管腔内牙本质中，照射组的 ν PO 值（1.23±0.06）低于未照射组（1.40±0.18）（P<0.05），而 ν PO 和 ν PO 峰无差异（P>0.05）。照射组（1.56±0.06）的碳酸盐、酰胺 III（1.05±0.19）和酰胺 I/III 比值（0.19±0.06）值低于未照射组（1.42±0.10、1.28±0.24 和 0.31±0.10）（P<0.05）。对于中牙本质照射组（1.30±0.12），磷酸盐值低于未照射组（1.48±0.22）（P<0.05）。在牙骨质中，两组之间无统计学差异。
放射治疗能引起根管牙本质 ν PO 、碳酸盐和酰胺 III 峰的变化。
