School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Republic of Korea; Amity Institute of Nanotechnology, Amity University, Uttar Pradesh, Sector 125, Noida 201303, India.
School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Republic of Korea.
J Microbiol Methods. 2019 Feb;157:65-80. doi: 10.1016/j.mimet.2018.12.008. Epub 2018 Dec 13.
The biosynthesis of nanomaterials is a huge and intensifying field of research due to their application in various areas, in particular the biomedical and pharmaceutical fields. In this review, we focused on the biosynthesis of both metallic and semiconductor nanomaterials and their application in biomedicine and pharmaceutics. In order to meet an exponentially increasing need for nanostructured materials, the biological route for the synthesis of nanomaterials will have to be explored, offering advantages over chemical and physical methods as a simpler, more cost effective, and environmentally friendly method, and for which there is no need to use high pressure and temperatures or toxic chemicals. This review discusses in detail the potential role of bioreducing and capping/stabilizing agents in biosynthesis. This review also investigates the application of various biosynthetic nanomaterials as antimicrobial materials, in clinical detection, for drug delivery and wound-healing, and as anti-diabetic materials.
由于纳米材料在各个领域，特别是在生物医药和制药领域的应用，其生物合成是一个巨大且日益增强的研究领域。在这篇综述中，我们专注于金属和半导体纳米材料的生物合成及其在生物医药和制药中的应用。为了满足对纳米结构材料的指数级增长的需求，必须探索纳米材料的生物合成途径，与化学和物理方法相比，这种方法作为一种更简单、更经济高效且环保的方法具有优势，并且不需要使用高压和高温或有毒化学品。本综述详细讨论了生物还原和封端/稳定试剂在生物合成中的潜在作用。本综述还研究了各种生物合成纳米材料作为抗菌材料、临床检测、药物输送和伤口愈合以及抗糖尿病材料的应用。
