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生物合成金属纳米粒子的最新趋势及其在生物医学中的应用:综述。

Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review.

机构信息

Faculty of Pharmacy, Integral University, Dasauli-Kursi Road, Lucknow, India.

Rameshwaram Institute of Technology and Management, Lucknow, 222620, India.

出版信息

Biol Trace Elem Res. 2024 Jul;202(7):3383-3399. doi: 10.1007/s12011-023-03920-9. Epub 2023 Oct 25.

Abstract

In recent years, biologically synthesized metal nanoparticles have emerged as a dynamic field of research with significant implications for biomedical applications. This review explores the latest trends in the synthesis of metal nanoparticles using biological methods, encompassing plant extracts and microorganisms such as bacteria, yeasts, and fungi. These innovative approaches offer a sustainable, cost-effective, and environmentally friendly alternative to conventional chemical synthesis methods. Moreover, this review delves into the multifaceted biomedical applications of biologically synthesized metal nanoparticles. These applications include drug delivery systems, diagnostics, therapeutics, and imaging technologies, showcasing the versatility and promise of these nanomaterials in addressing contemporary biomedical challenges. In addition, the review addresses the critical issue of cytotoxicity, offering insights into the safety and viability of these biologically derived NPs for medical use. The exploration of recent trends and advancements in this field underscores the transformative potential of biologically synthesized metal nanoparticles in revolutionizing biomedical research and healthcare.

摘要

近年来,生物合成的金属纳米粒子已经成为一个充满活力的研究领域,对生物医学应用具有重要意义。本综述探讨了使用生物方法合成金属纳米粒子的最新趋势,包括植物提取物和细菌、酵母和真菌等微生物。这些创新方法为传统的化学合成方法提供了一种可持续、经济高效和环保的替代方案。此外,本综述深入探讨了生物合成的金属纳米粒子在多方面的生物医学应用。这些应用包括药物传递系统、诊断、治疗和成像技术,展示了这些纳米材料在应对当代生物医学挑战方面的多功能性和潜力。此外,该综述还解决了细胞毒性这一关键问题,深入探讨了这些生物衍生的 NPs 在医学用途中的安全性和可行性。对该领域最新趋势和进展的探索强调了生物合成的金属纳米粒子在彻底改变生物医学研究和医疗保健方面的变革潜力。

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