Department of Chemistry , University of California , Berkeley , California 94720-1460 , United States.
Materials Sciences Division , Lawrence Berkeley National Laboratory , Berkeley , California 94720 , United States.
Chem Rev. 2019 Jan 9;119(1):700-726. doi: 10.1021/acs.chemrev.8b00381. Epub 2018 Dec 17.
Pathogenic bacteria have always posed one of the most serious threats to public health, and continue to be especially dangerous with the rise in antibiotic resistance. The prevalence of these infectious agents necessitates rapid, point-of-care sensors for their detection, identification, and monitoring. Electrochemical sensors are promising for the low-cost monitoring of bacterial growth and the detection of specific microbial species due to the consistency and ease-of-use of impedance measurements. Though the commercialization of these sensors is currently limited, they offer significant promise for detecting pathogens from real-world environments.
病原细菌一直对公众健康构成最严重的威胁之一,而抗生素耐药性的上升使其变得更加危险。这些传染病病原体的流行需要快速、即时的传感器来进行检测、识别和监测。电化学传感器由于阻抗测量的一致性和易用性,在低成本监测细菌生长和检测特定微生物物种方面具有广阔的应用前景。尽管这些传感器的商业化目前受到限制,但它们在从实际环境中检测病原体方面具有很大的潜力。