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基质辅助激光解吸电离飞行时间质谱法快速诊断人类血液中不常见的致病因 Anaerobiospirillum succiniciproducens。两例报告及文献复习。

MALDI-TOF MS for rapid diagnosis of Anaerobiospirillum succiniciproducens, an unusual causative agent of bacteraemia in humans. Two case reports and literature review.

机构信息

Clinical Microbiology Department, Hospital Universitario La Paz, Madrid, Spain.

Internal Medicine Department, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Anaerobe. 2019 Feb;55:130-135. doi: 10.1016/j.anaerobe.2018.12.003. Epub 2018 Dec 14.

DOI:10.1016/j.anaerobe.2018.12.003
PMID:30557657
Abstract

Anaerobiospirillum succiniciproducens is a gram-negative anaerobic spiral rod which is part of the normal flora of dogs and cats and can produce bacteraemia and diarrhoea in humans. In this report we describe two cases of bacteraemia caused by A. succiniciproducens which was successfully identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). We present a comprehensive literature review of 48 cases of A. succiniciproducens bacteraemia in which we describe previous underlying conditions, clinical presentations, identification methodology and antibiotic susceptibility data.

摘要

产琥珀酸厌氧螺旋菌是革兰氏阴性的厌氧螺旋杆菌,是犬猫正常菌群的一部分,可引起人类菌血症和腹泻。在本报告中,我们描述了两例由产琥珀酸厌氧螺旋菌引起的菌血症,该菌通过基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)成功鉴定。我们对 48 例产琥珀酸厌氧螺旋菌菌血症的病例进行了全面的文献回顾,描述了既往的基础疾病、临床表现、鉴定方法和抗生素药敏数据。

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MALDI-TOF MS for rapid diagnosis of Anaerobiospirillum succiniciproducens, an unusual causative agent of bacteraemia in humans. Two case reports and literature review.基质辅助激光解吸电离飞行时间质谱法快速诊断人类血液中不常见的致病因 Anaerobiospirillum succiniciproducens。两例报告及文献复习。
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