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2个月婴儿的不完全川崎病:病例报告

Incomplete Kawasaki disease in the 2-month-old infant: A case report.

作者信息

Ma Wei, Sun Juan, Wang Huaili

机构信息

Department of Pediatric Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Medicine (Baltimore). 2018 Dec;97(50):e13280. doi: 10.1097/MD.0000000000013280.

DOI:10.1097/MD.0000000000013280
PMID:30557973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6320020/
Abstract

RATIONALE

The diagnosis of Kawasaki disease (KD) is difficult and is often delayed for children whose age falls outside the typical age range of 6 months to 5 years, especially for those with incomplete KD (IKD) or atypical features.

PATIENT CONCERNS

A 2-month-20-day-old girl presented to our hospital with a chief complaint of intermittent fever for 1 day and 1 episode of seizure, with poor feeding and swelling of feet.

DIAGNOSIS

Until the appearance of red cracked lips, a diagnosis of IKD was considered. A rise in periungual desquamation of the hands confirmed the diagnosis.

INTERVENTIONS

Intravenous immunoglobulins were administered and aspirin and dipyridamole were used orally.

OUTCOME

The temperature, C-reactive protein, and erythrocyte sedimentation rate returned to normal level and there was no coronary artery lesion.

LESSONS

This case highlights that the diagnosis of IKD should be considered in children whose primary presentation is fever and neurologic features, lacking principal clinical findings, particularly those <6 months of age.

摘要

理论依据

川崎病(KD)的诊断较为困难,对于年龄不在6个月至5岁典型年龄范围内的儿童,尤其是不完全川崎病(IKD)或具有非典型特征的儿童,诊断往往会延迟。

患者情况

一名2个月20天大的女孩因间歇性发热1天和1次惊厥就诊于我院,伴有喂养困难和足部肿胀。

诊断

在出现红唇皲裂之前,考虑诊断为IKD。手部甲周脱皮增多证实了诊断。

干预措施

给予静脉注射免疫球蛋白,并口服阿司匹林和双嘧达莫。

结果

体温、C反应蛋白和红细胞沉降率恢复正常,未出现冠状动脉病变。

经验教训

该病例强调,对于以发热和神经系统特征为主、缺乏主要临床表现的儿童,尤其是年龄<6个月的儿童,应考虑IKD的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f655/6320020/13470f6a32d3/medi-97-e13280-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f655/6320020/13470f6a32d3/medi-97-e13280-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f655/6320020/13470f6a32d3/medi-97-e13280-g001.jpg

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本文引用的文献

1
Coronary Artery Aneurysms: A Review of the Epidemiology, Pathophysiology, Diagnosis, and Treatment.冠状动脉瘤:流行病学、病理生理学、诊断及治疗综述
Front Cardiovasc Med. 2017 May 5;4:24. doi: 10.3389/fcvm.2017.00024. eCollection 2017.
2
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association.川崎病的诊断、治疗和长期管理:美国心脏协会发布的一份面向医疗保健专业人员的科学声明。
Circulation. 2017 Apr 25;135(17):e927-e999. doi: 10.1161/CIR.0000000000000484. Epub 2017 Mar 29.
3
Prediction of Resistance to Intravenous Immunoglobulin in Children With Kawasaki Disease.
川崎病患儿静脉注射免疫球蛋白耐药的预测。
J Pediatric Infect Dis Soc. 2018 Feb 19;7(1):25-29. doi: 10.1093/jpids/piw075.
4
Kawasaki disease: insights into pathogenesis and approaches to treatment.川崎病:发病机制的深入了解和治疗方法。
Nat Rev Rheumatol. 2015 Aug;11(8):475-82. doi: 10.1038/nrrheum.2015.54. Epub 2015 Apr 28.
5
Kawasaki disease: pathophysiology, clinical manifestations, and management.川崎病:病理生理学、临床表现和治疗。
Curr Rheumatol Rep. 2014 Jun;16(6):423. doi: 10.1007/s11926-014-0423-x.
6
Diagnosis and classification of Kawasaki disease.川崎病的诊断和分类。
J Autoimmun. 2014 Feb-Mar;48-49:113-7. doi: 10.1016/j.jaut.2014.01.010. Epub 2014 Jan 28.
7
Intravenous immunoglobulin plus corticosteroid to prevent coronary artery abnormalities in Kawasaki disease: a meta-analysis.静脉注射免疫球蛋白联合皮质类固醇预防川崎病冠状动脉异常:荟萃分析。
Heart. 2013 Jan;99(2):76-82. doi: 10.1136/heartjnl-2012-302126. Epub 2012 Aug 6.
8
Hospitalizations for Kawasaki syndrome among children in the United States, 1997-2007.美国 1997-2007 年儿童川崎病住院情况。
Pediatr Infect Dis J. 2010 Jun;29(6):483-8. doi: 10.1097/INF.0b013e3181cf8705.
9
Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association.川崎病的诊断、治疗及长期管理:美国心脏协会青少年心血管疾病理事会风湿热、心内膜炎及川崎病委员会为卫生专业人员发布的声明
Pediatrics. 2004 Dec;114(6):1708-33. doi: 10.1542/peds.2004-2182.
10
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J Pediatr. 1997 Dec;131(6):888-93. doi: 10.1016/s0022-3476(97)70038-6.