HFIP 促进的 Bischler 吲哚合成在微波辐射下进行。
HFIP-Promoted Bischler Indole Synthesis under Microwave Irradiation.
机构信息
Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, South China Agricultural University, Guangzhou 510642, China.
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou 510642, China.
出版信息
Molecules. 2018 Dec 14;23(12):3317. doi: 10.3390/molecules23123317.
1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transformed into indole derivatives with moderate to good yields.
1,1,1,3,3,3-六氟-2-丙醇（HFIP）在微波辐射下，无需金属催化剂，即可有效用于 Bischler 吲哚合成。在 HFIP 的催化作用下，各种α-氨基芳基乙酮成功转化为吲哚衍生物，产率中等至良好。
Zotero 插件