Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.
Department of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia.
Int J Mol Sci. 2018 Dec 14;19(12):4060. doi: 10.3390/ijms19124060.
The auxin and ethylene pathways cooperatively regulate a variety of developmental processes in plants. Growth responses to ethylene are largely dependent on auxin, the key regulator of plant morphogenesis. Auxin, in turn, is capable of inducing ethylene biosynthesis and signaling, making the interaction of these hormones reciprocal. Recent studies discovered a number of molecular events underlying auxin-ethylene crosstalk. In this review, we summarize the results of fine-scale and large-scale experiments on the interactions between the auxin and ethylene pathways in Arabidopsis. We integrate knowledge on molecular crosstalk events, their tissue specificity, and associated phenotypic responses to decipher the crosstalk mechanisms at a systems level. We also discuss the prospects of applying systems biology approaches to study the mechanisms of crosstalk between plant hormones.
生长素和乙烯途径协同调节植物的多种发育过程。植物对乙烯的生长反应在很大程度上依赖于生长素，生长素是植物形态发生的关键调节剂。反过来，生长素能够诱导乙烯的生物合成和信号转导，使这些激素的相互作用具有互惠性。最近的研究发现了生长素-乙烯相互作用的许多分子事件。在这篇综述中，我们总结了在拟南芥中生长素和乙烯途径相互作用的精细和大规模实验的结果。我们整合了分子串扰事件、其组织特异性以及相关表型反应的知识，以在系统水平上破译串扰机制。我们还讨论了应用系统生物学方法来研究植物激素之间串扰机制的前景。
