Doğan A, Bayar Muluk N, Asal N, Şahan M H, Inal M, Gündüz Ö, Arıkan O K
Radiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Department of ENT, Faculty of Medicine, Kırıkkale University, Turkey.
J Laryngol Otol. 2018 Dec;132(12):1088-1092. doi: 10.1017/S0022215118002141. Epub 2018 Dec 18.
To investigate olfactory bulb volume and olfactory sulcus depth in patients with Behçet's disease, using magnetic resonance imaging.
Cranial magnetic resonance imaging scans of 27 adults with Behçet's disease (10 males and 17 females) and 27 healthy controls were examined. Olfactory bulb volume and olfactory sulcus depth were measured on coronal, T2-weighted, spectral pre-saturation with inversion recovery sequences.
Bilateral olfactory bulb volume and right-sided olfactory sulcus depth were significantly lower in the Behçet's disease group than in the control group (p < 0.05). Left-sided olfactory sulcus depth increased with Behçet's disease duration. In both groups, olfactory bulb volume was significantly higher in the left than the right side. There were no gender differences for olfactory bulb volume and olfactory sulcus depth. Positive correlations were determined between right- and left-sided olfactory bulb volume values and between right- and left-sided olfactory sulcus depth values.
Behçet's disease may decrease olfactory functions, related to lower olfactory bulb volume and olfactory sulcus depth. The affected vascular system and possibly damaged neural system, nasal mucosal lesions, and prolonged nasal mucociliary clearance time may cause olfactory dysfunction. Patient follow up is recommended, with magnetic resonance imaging examinations of the olfactory system if necessary.
利用磁共振成像研究白塞病患者的嗅球体积和嗅沟深度。
对27例白塞病成年患者（10例男性和17例女性）及27例健康对照者进行头颅磁共振成像扫描。在冠状面、T2加权、频谱预饱和反转恢复序列上测量嗅球体积和嗅沟深度。
白塞病组双侧嗅球体积和右侧嗅沟深度显著低于对照组（p < 0.05）。左侧嗅沟深度随白塞病病程增加。两组中，左侧嗅球体积均显著高于右侧。嗅球体积和嗅沟深度无性别差异。右侧和左侧嗅球体积值之间以及右侧和左侧嗅沟深度值之间存在正相关。
白塞病可能会降低嗅觉功能，这与嗅球体积减小和嗅沟深度变浅有关。受影响的血管系统以及可能受损的神经系统、鼻黏膜病变和延长的鼻黏液纤毛清除时间可能导致嗅觉功能障碍。建议对患者进行随访，必要时对嗅觉系统进行磁共振成像检查。
