Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT.
University of Connecticut School of Medicine, Farmington, CT.
J Arthroplasty. 2019 Mar;34(3):538-541. doi: 10.1016/j.arth.2018.11.037. Epub 2018 Nov 30.
Postoperative laboratory testing has been used routinely for patients undergoing total hip arthroplasty (THA). However, with modern-day improvements in perioperative care pathways, it is unclear whether this practice remains justified. The purpose of this study was to assess the utility of routine postoperative laboratory tests in primary THA.
The electronic medical records of 351 patients who underwent primary, unilateral THA between 2015 and 2017 were retrospectively reviewed. The primary outcomes were the rates of acute blood loss anemia requiring transfusion, acute kidney injury (AKI), electrolyte abnormalities, and 90-day emergency department visits or readmissions. Multivariate logistic regression analysis was also performed to identify the risk factors associated with abnormal laboratory values.
Seventy-four patients (21%) had abnormal postoperative laboratory results, of which 82.4% were exclusively due to electrolyte (sodium or potassium) abnormalities. Factors associated with electrolyte abnormalities were abnormal baseline electrolyte levels (P < .001 and P = .013 for sodium and potassium, respectively), diabetes (P = .007), and lack of tranexamic acid use (P < .01). The rates of AKI and blood transfusion were 2.0% and 2.3%, respectively. Factors associated with blood transfusion were higher American Society of Anesthesiologists class and intraoperative blood loss ≥250 mL combined with either preoperative anemia or lack of tranexamic acid use. Factors associated with AKI were higher American Society of Anesthesiologists class and diabetes. Laboratory results did not change the standard course of care in 338 of 351 patients (96%). Abnormal laboratory values were not associated with increased length of stay (P = .228) or emergency department visits/readmissions (P = .21).
This study provides evidence that routine postoperative laboratory testing is not necessary in modern-day primary, unilateral THA. Instead, the decision to obtain laboratory tests after surgery should be driven by patients' risk factors.
全髋关节置换术(THA)术后的实验室检测通常用于患者。然而,随着围手术期护理路径的现代改进,尚不清楚这种做法是否仍然合理。本研究旨在评估常规术后实验室检测在初次 THA 中的应用价值。
回顾性分析了 2015 年至 2017 年间接受初次单侧 THA 的 351 例患者的电子病历。主要结局是急性失血性贫血需要输血、急性肾损伤(AKI)、电解质异常以及 90 天内急诊就诊或再入院的发生率。还进行了多变量逻辑回归分析,以确定与异常实验室值相关的危险因素。
74 例(21%)患者术后实验室结果异常,其中 82.4%仅因电解质(钠或钾)异常所致。电解质异常的相关因素包括基线电解质水平异常(钠和钾分别为 P <.001 和 P =.013)、糖尿病(P =.007)和未使用氨甲环酸(P <.01)。AKI 和输血的发生率分别为 2.0%和 2.3%。输血的相关因素包括更高的美国麻醉医师协会(ASA)分级和术中出血量≥250 mL,同时伴有术前贫血或未使用氨甲环酸。AKI 的相关因素包括更高的 ASA 分级和糖尿病。在 351 例患者中的 338 例(96%)中,实验室结果并未改变标准治疗方案。异常实验室值与住院时间延长(P =.228)或急诊就诊/再入院(P =.21)无关。
本研究提供的证据表明,在现代初次单侧 THA 中,常规术后实验室检测并非必需。相反,术后进行实验室检测的决定应根据患者的危险因素做出。