多巴胺与饮食诱导的肥胖 - Suppr

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超能文献

Dopamine and diet-induced obesity.

作者信息

DiFeliceantonio Alexandra G, Small Dana M

机构信息

Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.

Modern Diet and PhysiologyResearch Center, YaleUniversity, New Haven, CT, USA.

出版信息

Nat Neurosci. 2019 Jan;22(1):1-2. doi: 10.1038/s41593-018-0304-0.

DOI:10.1038/s41593-018-0304-0

PMID:30559474

Abstract

摘要

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Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward.脂肪和碳水化合物联合摄入对食物奖赏的超相加效应。

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DRD2: Bridging the Genome and Ingestive Behavior.DRD2：连接基因组与摄食行为。

Trends Cogn Sci. 2017 May;21(5):372-384. doi: 10.1016/j.tics.2017.03.004. Epub 2017 Mar 31.

Long-term, calorie-restricted intake of a high-fat diet in rats reduces impulse control and ventral striatal D2 receptor signalling - two markers of addiction vulnerability.长期对大鼠进行高热量限制的高脂饮食摄入会降低冲动控制能力以及腹侧纹状体D2受体信号传导——这是成瘾易感性的两个指标。

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A gut lipid messenger links excess dietary fat to dopamine deficiency.一种肠道脂质信使将过量饮食脂肪与多巴胺缺乏联系起来。

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Decreased caudate response to milkshake is associated with higher body mass index and greater impulsivity.对奶昔的尾状核反应降低与更高的体重指数和更大的冲动性有关。

Physiol Behav. 2013 Sep 10;121:103-11. doi: 10.1016/j.physbeh.2013.03.025. Epub 2013 Apr 3.

High fat/carbohydrate ratio but not total energy intake induces lower striatal dopamine D2/3 receptor availability in diet-induced obesity.高脂肪/碳水化合物比例而非总能量摄入导致饮食诱导肥胖中纹状体多巴胺 D2/3 受体可用性降低。

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Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele.肥胖与纹状体对食物反应迟钝之间的关系受TaqIA A1等位基因的调节。

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