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多色光学相干断层扫描在视网膜病变诊断中的临床应用

Clinical application of multicolor optical coherence tomography in the diagnosis of retinal pathologies.

作者信息

Ghoghari Hunain, Rizvi Syed Fawad, Razzak Kaunain, Loya Hina

机构信息

Dr. Hunain Ghoghari, MBBS. Layton Rahamatullah Benevolent Trust (LRBT) Free Base Eye Hospital, Korangi 2 ½, Karachi, Pakistan.

Prof. Syed Fawad Rizvi, MCPS (ophth) FCPS (ophth). Layton Rahamatullah Benevolent Trust (LRBT) Free Base Eye Hospital, Korangi 2 ½, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2018 Nov-Dec;34(6):1555-1559. doi: 10.12669/pjms.346.16388.

DOI:10.12669/pjms.346.16388
PMID:30559822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6290197/
Abstract

OBJECTIVE

To assess the clinical application of multicolor optical coherence tomography (OCT) using confocal scanning laser ophthalmoscopy (cSLO) in different retinal pathologies.

METHODS

This observational study was conducted at the Layton Rahmatullah Benevolent Trust (LRBT), Free Base Eye Hospital, Karachi, from April 2018 to June 2018. It includes 36 patients suffering from different retinal pathologies including diabetic retinopathy, age related macular degeneration, and vitreomacular interface disorders using multicolor optical coherence tomography as a screening tool.

RESULTS

It was found that automated eye tracking system of this new version tool enables ophthalmologists to take high-resolution cSLO reflectance images. The light scatter can be avoided with the use of confocal optics. Appearances of pigment changes and hemorrhages were some of the differences found when compared to the conventional CFP. About 20% in AMD, 37.5% with diabetes and 100% patients with vitreomacular interface disorders could have be easily missed by CFP.

CONCLUSIONS

Multicolor OCT can provide information and figures far more authoritatively than the conventional CFP, which is highly affected by media opacities. To interpret Multicolor OCT ophthalmologists should be watchful with plenty of understanding.

摘要

目的

评估使用共焦扫描激光检眼镜（cSLO）的多色光学相干断层扫描（OCT）在不同视网膜病变中的临床应用。

方法

本观察性研究于2018年4月至2018年6月在卡拉奇自由基地眼科医院的莱顿·拉赫马图拉慈善信托基金（LRBT）进行。它包括36例患有不同视网膜病变的患者，包括糖尿病视网膜病变、年龄相关性黄斑变性和玻璃体黄斑界面疾病，使用多色光学相干断层扫描作为筛查工具。

结果

发现该新版本工具的自动眼跟踪系统使眼科医生能够获取高分辨率的cSLO反射图像。使用共焦光学系统可避免光散射。与传统的CFP相比，色素变化和出血的外观是发现的一些差异。在年龄相关性黄斑变性患者中约20%、糖尿病患者中37.5%以及玻璃体黄斑界面疾病患者中100%可能会被CFP轻易漏诊。

结论

多色OCT能够比受介质混浊影响很大的传统CFP更权威地提供信息和数据。为了解读多色OCT，眼科医生应具备充分的理解并保持警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/263ec6939abe/PJMS-34-1555-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/832455e404b6/PJMS-34-1555-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/3515322a4fbb/PJMS-34-1555-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/263ec6939abe/PJMS-34-1555-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/832455e404b6/PJMS-34-1555-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/3515322a4fbb/PJMS-34-1555-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b7/6290197/263ec6939abe/PJMS-34-1555-g003.jpg

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本文引用的文献

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Lasers Med Sci. 2018 Aug;33(6):1371-1379. doi: 10.1007/s10103-018-2498-5. Epub 2018 Apr 7.
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Multicolor Scanning Laser Imaging in Diabetic Retinopathy.
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VISUALIZATION OF MACULAR PUCKER BY MULTICOLOR SCANNING LASER IMAGING.多波长扫描激光成像对黄斑皱襞的显示。
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Ophthalmologica. 2016;236(1):8-18. doi: 10.1159/000446857. Epub 2016 Jul 13.
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Fundus Photography in the 21st Century--A Review of Recent Technological Advances and Their Implications for Worldwide Healthcare.21世纪的眼底摄影——近期技术进展及其对全球医疗保健影响的综述
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Scanning laser 'en face' retinal imaging of epiretinal membranes.视网膜前膜的扫描激光“正面”视网膜成像。
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