Mathisen Therese Fostervold, Bratland-Sanda Solfrid, Rosenvinge Jan H, Friborg Oddgeir, Pettersen Gunn, Vrabel Kari Anne, Sundgot-Borgen Jorunn
1Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.
Department of Sports and Physical Education and Outdoor Sciences, University of South-Eastern Norway, Bø in Telemark, Norway.
J Eat Disord. 2018 Dec 13;6:43. doi: 10.1186/s40337-018-0215-1. eCollection 2018.
Dysfunctional thoughts- and use of physical activity (PA) are core symptoms of the eating disorders (ED) bulimia nervosa (BN) and binge eating disorder (BED). The compulsive desire for PA complicates a favourable treatment outcome; hence, regular, adapted PA led by personnel with competence in exercise science is rarely part of treatment of BN and BED. The present study compared cognitive behaviour therapy (CBT) with a new treatment combining physical exercise and dietary therapy (PED-t) with respect to the short- and long-term changes in the level of compulsive exercise and actual level of PA in women with BN or BED.
We enrolled 187 women with BN or BED, aged 18-40 years, with BMI 17.5-35, in an outpatient randomised controlled therapy trial. Participants were randomised to PED-t or CBT, while waitlist participants served as a control group during the treatment period. The treatment covered 16 weeks, with 6- and 12 months follow-up, and outcomes included self-reported compulsive exercise (CE) and objectively measured PA, analysed by linear mixed regression models.
Both CBT and PED-t reduced CE from baseline ( < 0.01, Hedges ~ 0.4), but with no difference to control group. Compared to baseline, only PED-t significantly reduced the number of patients who scored above cut-off rating for CE, but with no between-group differences. The proportion of participants complying with the official recommendation for PA neither changed following treatment, nor emerged different between the treatment arms.
Both therapies resulted in significant improvements in compulsive exercise, a change not found in the control group, however there were no between-group differences. The findings are tempered by the low statistical power due to a small control group size. The number of participants complying with the recommendation for PA were stable throughout the study, and no change in total PA was found. Presence and intensity of CE decline with treatment, but a need to increase PA towards healthy levels remains unsolved.
Approved by the Norwegian Regional Committee for Medical and Health Research Ethics (ID: 2013/1871, 16th of December 2013); registered in Clinical Trials (ID: NCT02079935, 17th of February 2014).
功能失调性思维以及体育活动(PA)的使用是神经性贪食症(BN)和暴饮暴食症(BED)等饮食失调(ED)的核心症状。对体育活动的强迫性渴望会使良好的治疗结果变得复杂;因此,由具备运动科学专业能力的人员指导的规律、适度的体育活动很少成为BN和BED治疗的一部分。本研究比较了认知行为疗法(CBT)与一种将体育锻炼和饮食疗法相结合的新疗法(PED-t)在患有BN或BED的女性中,强迫性运动水平和实际体育活动水平的短期和长期变化。
我们招募了187名年龄在18至40岁、BMI为17.5至35的患有BN或BED的女性,进行一项门诊随机对照治疗试验。参与者被随机分配到PED-t组或CBT组,而等待名单上的参与者在治疗期间作为对照组。治疗为期16周,随访6个月和12个月,结果包括自我报告的强迫性运动(CE)和客观测量的体育活动,通过线性混合回归模型进行分析。
CBT和PED-t均使CE较基线水平降低(<0.01,Hedges's ~0.4),但与对照组相比无差异。与基线相比,只有PED-t显著降低了CE得分高于临界值的患者数量,但组间无差异。遵守体育活动官方建议的参与者比例在治疗后既未改变,治疗组之间也未出现差异。
两种疗法均使强迫性运动有显著改善,对照组未出现这种变化,然而组间无差异。由于对照组规模较小,统计功效较低,这使得研究结果受到影响。在整个研究过程中,遵守体育活动建议的参与者数量保持稳定,且未发现总体体育活动有变化。强迫性运动的存在和强度随治疗而下降,但将体育活动增加到健康水平的需求仍未得到解决。
经挪威医学和健康研究伦理区域委员会批准(编号:2013/1871,2013年12月16日);在临床试验注册中心注册(编号:NCT02079935,2014年2月17日)。