School of Software Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China.
Vascular surgery of Shanghai Sixth People's Hospital affiliated to Shanghai Jiao Tong University, Shanghai, 200233, China.
Sci Rep. 2018 Dec 18;8(1):17952. doi: 10.1038/s41598-018-36284-5.
Chronic venous insufficiency (CVI) affect a large population, and it cannot heal without doctors' interventions. However, many patients do not get the medical advisory service in time. At the same time, the doctors also need an assistant tool to classify the patients according to the severity level of CVI. We propose an automatic classification method, named CVI-classifier to help doctors and patients. In this approach, first, low-level image features are mapped into middle-level semantic features by a concept classifier, and a multi-scale semantic model is constructed to form the image representation with rich semantics. Second, a scene classifier is trained using an optimized feature subset calculated by the high-order dependency based feature selection approach, and is used to estimate CVI's severity. At last, classification accuracy, kappa coefficient, F1-score are used to evaluate classification performance. Experiments on the CVI images from 217 patients' medical records demonstrated superior performance and efficiency for CVI-classifier, with classification accuracy up to 90.92%, kappa coefficient of 0.8735 and F1score of 0.9006. This method also outperformed doctors' diagnosis (doctors rely solely on images to make judgments) with accuracy, kappa and F1-score improved by 9.11%, 0.1250 and 0.0955 respectively.
慢性静脉功能不全 (CVI) 影响着大量人群,如果没有医生的干预,它无法自行痊愈。然而,许多患者无法及时获得医疗咨询服务。与此同时,医生也需要一个辅助工具来根据 CVI 的严重程度对患者进行分类。我们提出了一种自动分类方法,称为 CVI-classifier,以帮助医生和患者。在这种方法中,首先,通过概念分类器将低级图像特征映射到中级语义特征,并构建多尺度语义模型,以形成具有丰富语义的图像表示。其次,使用基于高阶相关性的特征选择方法计算的优化特征子集来训练场景分类器,并用于估计 CVI 的严重程度。最后,使用分类准确率、kappa 系数和 F1 分数来评估分类性能。在来自 217 名患者病历的 CVI 图像上的实验表明,CVI-classifier 具有优越的性能和效率,分类准确率高达 90.92%,kappa 系数为 0.8735,F1 得分为 0.9006。该方法还优于医生的诊断(医生仅依靠图像进行判断),准确率、kappa 系数和 F1 得分分别提高了 9.11%、0.1250 和 0.0955。