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小分子 MERS-CoV 抑制剂的研发。

Development of Small-Molecule MERS-CoV Inhibitors.

机构信息

College of Life and Science, Hebei Agricultural University, Baoding 071001, China.

Research Center of Chinese Jujube, Hebei Agricultural University, Baoding 071001, China.

出版信息

Viruses. 2018 Dec 17;10(12):721. doi: 10.3390/v10120721.

DOI:10.3390/v10120721
PMID:30562987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6316138/
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) with potential to cause global pandemics remains a threat to the public health, security, and economy. In this review, we focus on advances in the research and development of small-molecule MERS-CoV inhibitors targeting different stages of the MERS-CoV life cycle, aiming to prevent or treat MERS-CoV infection.

摘要

中东呼吸综合征冠状病毒（MERS-CoV）有可能引发全球大流行，仍然对公共卫生、安全和经济构成威胁。在这篇综述中，我们专注于针对 MERS-CoV 生命周期不同阶段的小分子 MERS-CoV 抑制剂的研究和开发进展，旨在预防或治疗 MERS-CoV 感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/61b4238b2053/viruses-10-00721-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/a26ebe4513e5/viruses-10-00721-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/8139bda42eba/viruses-10-00721-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/329b1934304d/viruses-10-00721-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/4bc79297abaf/viruses-10-00721-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/61b4238b2053/viruses-10-00721-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/a26ebe4513e5/viruses-10-00721-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/8139bda42eba/viruses-10-00721-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/329b1934304d/viruses-10-00721-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/4bc79297abaf/viruses-10-00721-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e27e/6316138/61b4238b2053/viruses-10-00721-g005a.jpg

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