Farkas Balint, Szakacs Miklos
Department of Obstetrics and Gynecology, University of Pecs School of Medicine, 17 Edesanyak Str., Pecs, H-7624, Hungary.
MTA-PTE Human Reproduction Scientific Research Group, Hungarian Academy of Sciences (MTA), Pécs, Hungary.
J Med Case Rep. 2018 Dec 19;12(1):382. doi: 10.1186/s13256-018-1900-z.
Primary bladder neck obstruction is a rare clinical entity, reported to be responsible for 2.7-8% of lower urinary tract symptoms. It can lead to various urinary storage and voiding symptoms. The mainstay of treatment of female urethral strictures is urethral dilatation. Despite the long history of this method, it is unclear how far the female urethra should be dilated in correlation with residual urine volume.
A 79-year-old Caucasian woman presented to our institute with urgency (12-15 times/day), nocturia (3 times/night), and reoccurring urinary tract infections. A physical examination revealed no anatomical malformation in her genital organs, 150 mL post-void urine retention, and a significant narrowing in the mid-segment of the urethra (4 mm). After informed consent, our patient underwent urethral dilatation ranging from Ch9 (3 mm) to Ch39 (13 mm), and reported no symptoms at the 4-week follow-up, with no post-void residual urine.
The relatively low (around 50%) success rate of urethral dilatation might be improved by the utilization of wider dilatators, and the relaxation of the pubourethral ligament, achieved by a gentle downward saggital push during the intervention, although long-term studies with a large number of participants are necessary to prove our hypothesis.
原发性膀胱颈梗阻是一种罕见的临床病症,据报道占下尿路症状的2.7 - 8%。它可导致各种储尿和排尿症状。女性尿道狭窄的主要治疗方法是尿道扩张。尽管这种方法历史悠久,但尚不清楚女性尿道扩张程度与残余尿量之间的关系。
一名79岁的白人女性因尿急(每天12 - 15次)、夜尿(每晚3次)和反复尿路感染前来我院就诊。体格检查发现其生殖器官无解剖畸形,排尿后残余尿量为150 mL,尿道中段明显狭窄(4 mm)。在获得知情同意后,我们的患者接受了从Ch9(3 mm)到Ch39(13 mm)的尿道扩张,4周随访时报告无症状,且无排尿后残余尿。
使用更宽的扩张器以及在干预过程中通过轻柔的向下矢状推压使耻骨尿道韧带松弛,可能会提高尿道扩张相对较低(约50%)的成功率,不过需要大量参与者的长期研究来证实我们的假设。