创伤性脑损伤和慢性酒精中毒导致系列癫痫发作后苯妥英钠诱发的舞蹈手足徐动症。
Phenytoin-induced choreoathetosis after serial seizures due to traumatic brain injury and chronic alcoholism.
作者信息
Finsterer Josef, Keller Hans, Reining-Festa Alice, Enzelsberger Barbara, Weidinger Franz
机构信息
Krankenanstalt Rudolfstiftung Vienna Austria.
2nd Medical Department with Cardiology and Intensive Care Medicine Krankenanstalt Rudolfstiftung Vienna Austria.
出版信息
Clin Case Rep. 2018 Oct 17;6(12):2316-2318. doi: 10.1002/ccr3.1870. eCollection 2018 Dec.
Abstract
Intravenous phenytoin (PHT) for suspected seizures may trigger severe choreoathetosis. Discontinuation of PHT results in immediate and complete resolution of hyperkinesias. Co-medication with valproic acid, levetiracetam, tranquilisers, and anesthetics or alcohol presumably do not modify this adverse effect of PHT. Choreoathetosis can be easily misinterpreted as seizures.
摘要
静脉注射苯妥英钠（PHT）用于疑似癫痫发作时可能引发严重的舞蹈手足徐动症。停用PHT可使运动障碍立即完全缓解。与丙戊酸、左乙拉西坦、镇静剂、麻醉剂或酒精联合用药可能不会改变PHT的这种不良反应。舞蹈手足徐动症很容易被误诊为癫痫发作。
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