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乳房手术后坏疽性脓皮病:需要早期诊断和正确治疗。

Post-surgical pyoderma gangrenosum of the breast: needs for early diagnosis and right therapy.

机构信息

Division of Medical Oncology, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Via Del Pozzo 71, Modena, Italy.

Oncologic Breast Surgery Unit, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena, Modena, Italy.

出版信息

Breast Cancer. 2019 Jul;26(4):520-523. doi: 10.1007/s12282-018-00940-5. Epub 2018 Dec 18.

DOI:10.1007/s12282-018-00940-5
PMID:30564995
Abstract

Post-surgical pyoderma gangrenosum (PSPG) of the breast is a rare dermatosis that worsens surgical manipulation, with a chronical relapsing course. Diagnosis is mostly clinical and made by exclusion after the failure of antibiotic therapies and surgical debridement, while the mainstay of therapy is corticosteroid-based. Here we report a case of PSPG of the breast in a young woman with breast cancer, to emphasize the needs of an early and accurate diagnosis, to guarantee the most efficacious treatment and to avoid life-threatening complications.

摘要

乳房手术后坏疽性脓皮病(PSPG)是一种罕见的皮肤病,会因手术操作而恶化,呈慢性复发性病程。诊断主要依靠临床检查,并在抗生素治疗和外科清创失败后通过排除法得出,而治疗的主要手段是基于皮质类固醇的治疗。在此,我们报告了一例年轻女性乳腺癌合并乳房 PSPG 的病例,以强调早期准确诊断的必要性,以确保最有效的治疗并避免危及生命的并发症。

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本文引用的文献

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Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts.溃疡性坏疽性脓皮病的诊断标准:国际专家德尔菲共识。
JAMA Dermatol. 2018 Apr 1;154(4):461-466. doi: 10.1001/jamadermatol.2017.5980.
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Hyperbaric oxygen therapy for pyoderma gangrenosum associated with ulcerative colitis.高压氧疗法治疗与溃疡性结肠炎相关的坏疽性脓皮病。
Intest Res. 2018 Jan;16(1):155-157. doi: 10.5217/ir.2018.16.1.155. Epub 2018 Jan 18.
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Pyoderma Gangrenosum after Deep Inferior Epigastric Perforator Breast Reconstruction: Systematic Review and Case Report.
乳房切除术后坏疽性脓皮病的管理
Plast Reconstr Surg Glob Open. 2022 Apr 25;10(4):e4282. doi: 10.1097/GOX.0000000000004282. eCollection 2022 Apr.
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Dermatologic Complications Following Cosmetic and Reconstructive Plastic Surgery: A Systematic Review of the Literature.美容与重建整形外科术后的皮肤并发症:文献系统回顾。
Aesthetic Plast Surg. 2021 Dec;45(6):3005-3018. doi: 10.1007/s00266-021-02362-9. Epub 2021 Jul 6.
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Post Reduction Mammaplasty Pyoderma Gangrenosum: An Unusual Presentation of a Misdiagnosed Entity.乳房缩小成形术后坏疽性脓皮病:一种误诊疾病的罕见表现。
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A systematic review of post-surgical pyoderma gangrenosum: identification of risk factors and proposed management strategy.术后坏疽性脓皮病的系统评价:危险因素识别及建议的管理策略
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Am J Clin Dermatol. 2014 Oct;15(5):413-23. doi: 10.1007/s40257-014-0092-6.
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