Huang Lin, Chen Ke-Liang, Lin Bi-Ying, Tang Le, Zhao Qian-Hua, Li Fang, Guo Qi-Hao
Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Department of Gerontology, Fuxing Hospital, Capital Medical University, Beijing, China.
Int Psychogeriatr. 2019 Jun;31(6):849-856. doi: 10.1017/S1041610218001230.
To revise an abbreviated version of the Silhouettes subtest of the Visual Object and Space Perception (VOSP) battery in order to recognize mild cognitive impairment (MCI) and determine the optimal cutoffs to differentiate among cognitively normal controls (NC), MCI, and Alzheimer's Disease (AD) in the Chinese elderly.
A cross-sectional validation study.
Huashan Hospital, Shanghai, China.
A total of 591 participants: Individuals with MCI (n = 211), AD (n = 139) and NC (n = 241) were recruited from the Memory Clinic, Huashan Hospital, Shanghai, China.
Baseline neuropsychological battery (including VOSP) scores were collected from firsthand data. An abbreviated version of silhouettes test (Silhouettes-A) was revised from the original English version more suitable for the elderly, including eight silhouettes of animals and seven silhouettes of inanimate objects, with a score ranging from 0 to 15.
Silhouettes-A was an effective test to screen MCI in the Chinese elderly with good sensitivity and specificity, similar to the Montreal cognitive assessment and superior to other single tests reflecting language, spatial, or executive function. However, it had no advantage in distinguishing MCI from AD. The corresponding optimal cutoff scores of Silhouettes-A were 10 for screening MCI and 8 for AD.
Silhouettes-A is a quick, simple, sensitive, and dependable cognitive test to distinguish among NC, MCI, and AD patients.
修订视觉物体与空间感知(VOSP)成套测验中轮廓分测验的简略版,以识别轻度认知障碍(MCI),并确定中国老年人中认知正常对照(NC)、MCI和阿尔茨海默病(AD)之间进行区分的最佳临界值。
一项横断面验证研究。
中国上海华山医院。
共591名参与者:MCI患者(n = 211)、AD患者(n = 139)和NC(n = 241),均来自中国上海华山医院记忆门诊。
从第一手数据中收集基线神经心理成套测验(包括VOSP)分数。对轮廓测验的简略版(轮廓-A)进行修订,使其从原始英文版更适合老年人,包括八个动物轮廓和七个无生命物体轮廓,分数范围为0至15分。
轮廓-A是筛查中国老年人MCI的有效测验,具有良好的敏感性和特异性,与蒙特利尔认知评估相似,优于其他反映语言、空间或执行功能的单项测验。然而,在区分MCI和AD方面它没有优势。轮廓-A筛查MCI和AD的相应最佳临界值分别为10分和8分。
轮廓-A是一种快速、简单、敏感且可靠的认知测验,可用于区分NC、MCI和AD患者。