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一名早产双胞胎女婴出现与内脏型婴儿血管瘤相关的反复便血。

Recurrent bloody stools associated with visceral infantile haemangioma in a preterm twin girl.

作者信息

Krick Jeanne, Riehle Kimberly, Chapman Teresa, Chabra Shilpi

机构信息

Neonatology, University of Washington, Seattle, Washington, USA.

Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, Washington, USA.

出版信息

BMJ Case Rep. 2018 Dec 3;11(1):bcr2018226564. doi: 10.1136/bcr-2018-226564.

Abstract

A premature twin infant girl was transferred to a level IV neonatal intensive care unit for recurrent bloody stools, anaemia and discomfort with feeds; without radiographic evidence of necrotising enterocolitis. Additional imaging after transfer revealed a large retroperitoneal mass in the region of the pancreas compressing the inferior vena cava and abdominal aorta, raising suspicion for neuroblastoma. Abdominal exploration and biopsy unexpectedly revealed that the lesion was an infantile capillary haemangioma involving the small bowel, omentum, mesentery and pancreas. The infant was subsequently treated with propranolol, with a decrease in the size of the lesion over the first year of her life and a drastic improvement in feeding tolerance. While cutaneous infantile haemangiomas are common, visceral infantile haemangiomas are less so and may present a significant diagnostic challenge for clinicians. This interesting case demonstrates that such lesions should be considered in the differential diagnosis for unexplained gastrointestinal bleeding or abdominal symptoms in newborns.

摘要

一名早产双胎女婴因反复便血、贫血及喂养不适被转至四级新生儿重症监护病房;影像学检查未发现坏死性小肠结肠炎证据。转院后进一步影像学检查显示胰腺区域有一个巨大的腹膜后肿块,压迫下腔静脉和腹主动脉,高度怀疑为神经母细胞瘤。腹部探查及活检意外发现该病变为累及小肠、大网膜、肠系膜和胰腺的婴儿型毛细血管瘤。该婴儿随后接受了普萘洛尔治疗,在其出生后的第一年里病变大小减小,喂养耐受性显著改善。虽然皮肤型婴儿血管瘤很常见,但内脏型婴儿血管瘤较少见,可能给临床医生带来重大诊断挑战。这个有趣的病例表明,对于新生儿不明原因的胃肠道出血或腹部症状,鉴别诊断时应考虑此类病变。

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Infantile haemangioma.婴儿血管瘤。
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Visceral and mucosal involvement in neonatal haemangiomatosis.新生儿血管瘤病的内脏和黏膜累及。
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