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Open Forum Infect Dis. 2017 Feb 22;4(2):ofx035. doi: 10.1093/ofid/ofx035. eCollection 2017 Spring.
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N Engl J Med. 2017 Jun 8;376(23):2223-2234. doi: 10.1056/NEJMoa1701380. Epub 2017 Mar 21.
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Intensive Care Med. 2017 May;43(5):625-632. doi: 10.1007/s00134-016-4675-y. Epub 2017 Jan 27.
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A users' guide to the 2016 Surviving Sepsis Guidelines.《2016年拯救脓毒症指南用户指南》
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Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association.成人感染性心内膜炎:诊断、抗菌治疗和并发症处理:美国心脏协会医疗保健专业人员科学声明。
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一名患有心内膜炎的患者中,严重主动脉瓣反流被误诊为脓毒症诱发的急性呼吸窘迫综合征。

Severe aortic regurgitation masked as sepsis-induced ARDS in a patient with endocarditis.

作者信息

Lamaa Nader, Bromberg Romina, Foroughi Maryam, Danckers Mauricio

机构信息

Internal Medicine, Aventura Hospital and Medical Center, Aventura, Florida, USA.

出版信息

BMJ Case Rep. 2018 Dec 4;11(1):e226681. doi: 10.1136/bcr-2018-226681.

DOI:10.1136/bcr-2018-226681
PMID:30567191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6301507/
Abstract

Septic shock is the most common type of shock in the intensive care unit with an associated mortality close to 50%. Infective endocarditis (IE) is a rare cause of septic shock but carries significant morbidity and mortality. Group B IE (GBS-IE) is an invasive infection with an incidence of approximately 1.7%. It affects immunocompromised patients such as intravenous drug users, alcoholics, those with HIV and elderly among others. IE with severe acute valvular heart disease challenges physicians when assessing fluid status during the early resuscitation in patients with septic shock. We present a case of GBS-IE complicated by severe acute aortic regurgitation with rapidly progressive acute respiratory failure in the setting of septic shock management.

摘要

感染性休克是重症监护病房中最常见的休克类型,其相关死亡率接近50%。感染性心内膜炎(IE)是感染性休克的罕见病因,但具有显著的发病率和死亡率。B组IE(GBS-IE)是一种侵袭性感染,发病率约为1.7%。它影响免疫功能低下的患者,如静脉吸毒者、酗酒者、艾滋病毒感染者和老年人等。在感染性休克患者的早期复苏过程中,伴有严重急性瓣膜性心脏病的IE在评估液体状态时给医生带来了挑战。我们报告一例GBS-IE合并严重急性主动脉瓣反流,并在感染性休克管理过程中迅速进展为急性呼吸衰竭的病例。